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  • Construção, adaptação transcultural e adequação de instrumentos de medida
    Publication . Marques-Vieira, Cristina Maria Alves; Sousa, Luís Manuel Mota de; Carvalho, Maria Leonor Ramos; Veludo, Filipa; José, Helena Maria Guerreiro
    Objective: this is the first of two articles which intend to systematize the stages covered by the investigator in the elaboration, adequacy and validation of the instruments of measurement which are auto-complete. Methodology: a review of the literature was done, using manuals and international data bases. Results: in this paper special emphasis is given towards the construction and adequacy of the instruments of measurement, its transcultural adaptation, as well as, the criteria used in decision making when a fidelity and validation analysis of the instruments is performed. Conclusion: the instruments of measurement must be precise and validated in order to guarantee the reliability of the results.
  • Fidelidade e validade na construção e adequação de instrumentos de medida
    Publication . Sousa, Luís Manuel Mota de; Marques-Vieira, Cristina Maria Alves; Carvalho, Maria Leonor Ramos; Veludo, Filipa; José, Helena Maria Guerreiro
    Objetivo: este artigo tem como objetivo sistematizar as primeiras etapas percorridas pelo investigador na elaboração, no processo de adequação e validação de instrumentos de medida de autopreenchimento. Método: para o efeito foi realizada uma revisão da literatura, recorrendo à consulta de manuais e à pesquisa em bases de dados internacionais. Resultados: neste artigo dá-se especial enfoque à análise da fidelidade e validade dos referidos instrumentos de medida. Realça-se, também, a utilização da análise fatorial exploratória e confirmatória para a validação de construto. Conclusão: os instrumentos de medida devem ser precisos e validados, de modo a garantir a fiabilidade dos resultados.
  • Development of the EMHA migraine scoring system
    Publication . Goadsby, Peter J.; Irimia, Pablo; Terwindt, Gisela M.; Mitsikostas, Dimos; Ashina, Messoud; Brink, Antoinette Maassen van den; Lampl, Christian; Gil-Gouveia, Raquel; Amin, Faisal Mohammad; Torre, Elena Ruiz de la; Caronna, Edoardo; Hurtado, David; Fairley, Carmen; Pozo-Rosich, Patricia
  • Virtual reality in undergraduate operating theatre nursing education: a scoping review protocol
    Publication . Moura, Carina; Pegado, Ana; Alves, José; Neves, Vasco; Alves, Paulo
    Introduction: Virtual reality has emerged as an innovative tool in nursing education, enabling immersive and interactive learning experiences that may support the development of technical and non-technical skills. In undergraduate training, access to real surgical environments is often restricted due to safety, ethical and logistical concerns, which limits experiential learning in the operating theatre. Virtual reality may represent a valuable complement; however, current evidence is dispersed and has not yet been systematically summarized, justifying the need to map existing knowledge. Objectives: To map the published evidence on the use of virtual reality in undergraduate nursing education within the operating theatre context, identifying modalities, educational purposes, learning outcomes, and existing research gaps. Methodology: Following Joanna Briggs Institute methodology and PRISMA-ScR reporting guidelines, this scoping review will comprehensively map the existing evidence on the use of virtual reality (Concept) in undergraduate nursing education (Population) within the operating theatre setting (Context). Searches will be conducted in MEDLINE (via PubMed), Scopus, Web of Science, CINAHL Complete, SciELO and the Cochrane Library. Grey literature will also be systematically explored through multiple sources, including Repositório Científico de Acesso Aberto de Portugal, international dissertation and thesis repositories such as ProQuest Dissertations & Theses Global, and websites of relevant professional organizations and academic institutions. Study selection and data extraction will be carried out independently by two reviewers using a pre-designed tool, and the findings will be synthesized descriptively, supported using charts and tables to map key concepts, evidence types, and research gaps. Results: The review is expected to map virtual reality technologies, educational approaches, competencies targeted, and measured outcomes in undergraduate perioperative nursing education, as well as research gaps and methodological limitations. Conclusion: This protocol supports the transparent and rigorous development of a scoping review on virtual reality in undergraduate operating theatre nursing education. The expected findings may inform educational planning, guide simulation design and support future research in perioperative nursing education.
  • Educational applications of AI-based chatbots in nursing: a scoping review
    Publication . Fernandes, Francisco; Encarnação, Rúben; Alves, José; Pais-Vieira, Carla; Lima, Suzinara Beatriz Soares de; Alves, Paulo
    Background/Objectives: The rapid expansion of generative artificial intelligence (AI) and large language model-based chatbots has accelerated their adoption in higher education, including nursing. This scoping review mapped the use of AI-based chatbots in nursing education, including curricular domains, pedagogical approaches, educational outcomes, and implementation challenges. Methods: A scoping review was conducted following the Joanna Briggs Institute methodology and reported in accordance with the PRISMA-ScR guideline. Searches were performed across major bibliographic databases and grey literature sources. Quantitative, qualitative, and mixed-methods studies addressing the use of AI chatbots in nursing education or professional training were included. Data were extracted using a standardized instrument and synthesized through descriptive statistics and qualitative content analysis. Results: Sixty-six studies (2019–2025) were included, with significant growth observed after 2023. Most studies employed quasi-experimental designs (37.9%) and were implemented in academic settings (83.3%). Application formats varied across online, hybrid, simulation-based, and classroom models. Reported benefits included improved learning performance, clinical reasoning, and student engagement. Key challenges involved the reliability of AI outputs, academic integrity, data protection, and limited institutional governance. Conclusions: AI-based chatbots represent promising tools to enhance nursing education, particularly when integrated into structured pedagogical strategies with active faculty supervision. Their use can support the development of clinical reasoning, student engagement, and personalized learning. However, methodological heterogeneity, ethical concerns, and governance gaps highlight the need for careful implementation and further rigorous research to ensure safe, effective, and pedagogically sound integration.
  • The effectiveness of NIRS technology to the early diagnosis of lower limb ischemia in patients on peripheral VA ECMO: a systematic review and meta-analysis
    Publication . Coelho, Raquel; Tavares, Joana; Marinheiro, Catarina; Costa, Carina; Gregório, Tiago; Ferreira, Simão
    Background: Acute lower limb ischemia is a major complication of peripheral venoarterial ECMO, significantly impacting patient outcomes and survival rates. Traditional methods for assessing limb perfusion, such as physical exams and Doppler ultrasound, are often unreliable and do not provide continuous monitoring. Near-infrared spectroscopy (NIRS), a non-invasive technique, shows promise for perfusion monitoring in venoarterial ECMO patients, but its effectiveness in the early detection of limb hypoperfusion remains unreviewed. Aim: Evaluate the effectiveness of NIRS technology in the early diagnosis of lower limb ischemia in patients undergoing peripheral VA ECMO. Methods: The search strategy covered five databases. Inclusion criteria included studies in Portuguese, English, Spanish, or German involving participants aged 18 or older dependent on peripheral VA ECMO. The intervention assessed was limb perfusion monitoring using NIRS in VA ECMO patients. The primary outcome was the effectiveness of NIRS in the early diagnosis of limb ischemia. Exclusion criteria included review articles, book chapters, books, editorials, conference papers, and studies on pediatric patients, central VA ECMO, or venovenous ECMO. Study quality was evaluated using the ROBINS-I tool. Meta-analysis was performed using R package meta. Narrative synthesis was applied when meta-analysis was unfeasible. Results: Of 180 studies, 164 were excluded after initial screening. Of the remaining 16 studies, eight were removed for irrelevance, high bias risk, or pediatric focus, leaving eight studies. The results revealed a pooled sensitivity of the diagnostic method of 0.71 (95% CI: [0.67, 0.74]) and a pooled specificity of 0.68 (95% CI: [0.61, 0.74]). Conclusions: NIRS technology is an effective diagnostic tool for reliably detecting true positive cases of limb ischemia. Implications for Clinical Practice: The decrease in NIRS values and the difference between limbs may indicate hypoperfusion, requiring further investigation. NIRS also helps assess distal perfusion catheter functionality, enhancing our ability to provide safe, high-quality care.
  • Análise antropométrica dos dentes ântero-superiores numa população de Viseu
    Publication . Nikulina, Miroslava Stefanova; Araújo, Filipe; Fialho, Joana; Salgado, Helena
    Objetivos: Nos últimos anos, a Medicina Dentária tem dado uma atenção crescente aos componentes estéticos na sua prática e aplicação clínica, refletindo a valorização do sorriso na imagem pessoal. A Reabilitação Oral, que anteriormente se centrava sobretudo no restabelecimento da função mastigatória, passou também a englobar critérios estéticos rigorosos, visando atender às crescentes exigências e expectativas dos pacientes. Neste contexto, os dentes ântero-superiores assumem um papel dominante na composição do sorriso, estando intrinsecamente ligados à sua harmonia. O principal objetivo deste trabalho é analisar as caraterísticas antropométricas e a existência de Proporção Dourada entre os dentes ântero-superiores na amostra em estudo. Materiais e métodos: Foram analisados modelos digitais da maxila, obtidos através de scanner intraoral de 82 indivíduos que cumpriam com os critérios de inclusão e exclusão definidos. Após importação no programa Blender, foram realizadas as medições das dimensões dentárias, nomeadamente a largura e a altura das coroas dos dentes ântero-superiores. Os dados obtidos foram sujeitos a uma análise estatística descritiva e inferencial, com um limiar de significância de p<0,05. Resultados: A análise antropométrica demonstrou diferenças estatisticamente significativas em todas as variáveis das dimensões dentárias entre os sexos biológicos (p<0,05). Foram igualmente demonstradas assimetrias dimensionais entre dentes contralaterais, confirmadas pelos testes T de amostras emparelhadas. Os valores da proporção altura-largura das coroas dentárias dos Incisivos Centrais foram superiores ao Golden Standard, que preconiza valores entre 75% e 80%. Foram relatadas diferenças estatisticamente significativas entre o valor real e o valor esperado das larguras aparentes das coroas dentárias em todos os dentes analisados, o que demonstra a ausência de Proporção Dourada. Conclusões: A análise antropométrica permitiu confirmar a existência de dimorfismo sexual e de assimetrias entre dentes contralaterais. Apesar da estética dentária estar relacionada com padrões estéticos pré-definidos, como são exemplo o Golden Standard e a Proporção Dourada, estes não foram verificados na amostra em estudo.
  • A relação das má-oclusões com as desordens temporomandibulares
    Publication . Oliveira, Ana Rita; Carvalho, Rita; Fonseca, Patrícia; Silva, Susana
  • Exploring the effect of flavonoid-based solutions or formulations as antibiofilm agents in endodontics: a scoping review
    Publication . Nunes, Gabriel Pereira; Saint-Etienne, Elise; Mello-Moura, Anna Carolina Volpi; Danelon, Marcelle; Sterzenbach, Torsten; Hannig, Christian; Alves, Renata Toledo; Duque, Cristiane
    Objective This scoping review aimed to map and summarize the evidence on the antimicrobial and antibiofilm efficacy of flavonoid-based solutions or formulations for endodontic applications. Design The review was conducted in accordance with the PRISMA-ScR guidelines. A comprehensive search was performed across databases for articles published up to April 2025. Eligible studies included those evaluating the antimicrobial effects of flavonoids on microorganisms associated with endodontic infections. Relevant data were extracted, and a descriptive synthesis of the findings was carried out. Results The results showed that fifteen studies met the inclusion criteria, demonstrating significant antimicrobial and antibiofilm activity of various flavonoids. Epigallocatechin-3-gallate was the most extensively studied compound, showing dose-dependent activity against E. faecalis, F. nucleatum, A. israelii, S. mutans, and C. albicans, with enhanced efficacy when combined with agents such as fosfomycin or the peptide KR-12-a5. Quercetin also displayed concentration-dependent antibiofilm effects and gene modulation in E. faecalis. Proanthocyanidin showed superior efficacy compared to conventional irrigants, especially at higher concentrations. Rutin, although limited in standalone efficacy, showed promising results when used as a photosensitizer. Other flavonoids such as apigenin, theaflavin, isoquercitrin, ampelopsin, chalcone, and chrysin also demonstrated varying degrees of antimicrobial activity, often similar to or surpassing conventional agents like chlorhexidine and calcium hydroxide in specific models. Conclusions Flavonoids exhibit significant potential as alternative or adjunctive agents for endodontic disinfection, especially in biofilm-related infections. Their efficacy is influenced by compound type, concentration, formulation, and synergistic combinations. Further research, especially clinical trials, is warranted to validate their therapeutic applicability and optimize delivery systems for clinical use in endodontics.
  • Análise da rugosidade de superfície de resinas de provisórios em prótese fixa
    Publication . Santos, Miguel Pina; Fonseca, Patrícia; Fernandes, Carlos; Lourinho, Cláudia; Quezada, Margarida; Salgado, Helena
    Objetivos: Atualmente para a confeção de provisórios em prótese fixa existem diferentes resinas que vão desde as mais convencionais em polimetilmetacrilato até às mais modernas adaptadas às novas tecnologias digitais. O principal objetivo deste estudo laboratorial é determinar a rugosidade média de superfície de diferentes tipos de resina utilizados na confeção de provisórios fixos. Materiais e métodos: Esta investigação consistiu num estudo laboratorial in vitro para avaliar uma das propriedades físicas de superfície dos materiais, a rugosidade de superfície. Foram utilizados 4 tipos de resinas, uma resina acrílica de polimetilmetacrilato (Tab 2000), uma resina bis-acrílica (Structur 3), uma resina de fresagem (Structur CAD) e uma resina de impressão 3D (Dental Sand). A amostra foi constituída por cinco provetes de cada resina, de forma quadrangular e com dimensões padronizadas: 20x20x2mm. Após a sua confeção, os provetes de cada resina foram submetidos ao mesmo protocolo de polimento, procurando-se assim simular o polimento realizado em consultório, de forma homogénea e independente da resina testada. Posteriormente, os provetes foram deixados em água destilada a 37ºC durante 24 horas para simular a hidratação em ambiente oral. A medição da rugosidade média foi realizada utilizando um perfilómetro de contacto. Foram realizadas 6 medições: 3 verticais e 3 horizontais, em locais diferentes de cada provete e calculado o valor médio de rugosidade. Os valores obtidos foram sujeitos a análise estatística descritiva e inferencial, com um limiar de significância estatística de p<0,05. Resultados: Os valores mais baixos de rugosidade foram registados na resina de fresagem (0,303µm) e os mais elevados na resina bis-acrílica (0.686µm), com diferenças estatisticamente significativas. Diferenças com significância estatística foram também encontradas entre a resina de fresagem e a de impressão 3D e entre a resina acrílica e a bis-acrílica. Por outro lado, a resina impressa e a bis-acrílica, assim como a fresada e a impressa comparativamente ao polimetilmetacrilato não diferiram entre si de forma significativa. Conclusões: Este trabalho de investigação permitiu verificar que a resina bis-acrílica utlizada neste estudo, considerando apenas a rugosidade de superfície, do ponto de vista biológico deverá ser a resina com maior probabilidade de adesão microbiana. Por outro lado, a resina de fresagem poderá ser biologicamente uma boa opção clínica para provisórios de longa duração.