Browsing by Author "Canaipa, Rita"
Now showing 1 - 9 of 9
Results Per Page
Sort Options
- Can health care providers recognise a fibromyalgia personality?Publication . Silva, José A. P. da; Jacobs, Johannes W. G.; Branco, Jaime C.; Canaipa, Rita; Gaspar, M. Filomena; Griep, Ed N.; Helmond, T. van; Oliveira, Paula J.; Zijlstra, T. R.; Geenen, RinieOBJECTIVES: To determine if experienced health care providers (HCPs) can recognise patients with fibromyalgia (FM) based on a limited set of personality items, exploring the existence of a FM personality. METHODS: From the 240-item NEO-PI-R personality questionnaire, 8 HCPs from two different countries each selected 20 items they considered most discriminative of FM personality. Then, evaluating the scores on these items of 129 female patients with FM and 127 female controls, each HCP rated the probability of FM for each individual on a 0-10 scale. Personality characteristics (domains and facets) of selected items were determined. Scores of patients with FM and controls on the eight 20-item sets, and HCPs’ estimates of each individual’s probability of FM were analysed for their discriminative value. RESULTS: The eight 20-item sets discriminated for FM, with areas under the receiver operating characteristic curve ranging from 0.71-0.81. The estimated probabilities for FM showed, in general, percentages of correct classifications above 50%, with rising correct percentages for higher estimated probabilities. The most often chosen and discriminatory items were predominantly of the domain neuroticism (all with higher scores in FM), followed by some items of the facet trust (lower scores in FM). CONCLUSIONS: HCPs can, based on a limited set of items from a personality questionnaire, distinguish patients with FM from controls with a statistically significant probability. The HCPs’ expectation that personality in FM patients is associated with higher levels for aspects of neuroticism (proneness to psychological distress) and lower scores for aspects of trust, proved to be correct.
- En pointe: dancers report their pain less variably than do controlsPublication . Canaipa, Rita; Mendonça, Diogo; Agostinho, Mariana; Nascimento, Vanda; Honigman, Liat; Treister, RoiThe subjective nature of pain and the lack of a gold standard for objective measurement hinders effective assessment, diagnosis, and treatment. Some individuals, such as professional dancers, are better in assessing and reporting bodily sensations. This observational study aimed to assess whether dancers report their pain less variably, than other people do. After consenting, subjects completed the focused analgesia selection test (FAST), which assesses subjects’ variability of pain reports. FAST outcomes, ICC and R2 reflect the magnitude of variability of pain reports observed. In addition, subjects underwent a taste task, which similarly assesses variability of tastes (salty and sweet) intensity reports and completed the Multidimensional Assessment of Interoceptive Awareness questionnaire. Thirty-three professional dancers and 33 healthy aged-matched controls were recruited. The dancers exhibited less variability of pain reports then controls (P = .013), but not in case of tastes-reports. Years of practice was positively correlated with pain reporting variability (r = .447, P = .009, and r = .380, P = .029; for FAST ICC and R2, respectively). Multidimensional Assessment of Interoceptive Awareness subscores correlated with pain reporting variability: R2 and ICC with emotional awareness (r = .260, P = .040, and r = .274, P = .030, respectively), and R2 with trusting [r = .254, P = .044]). Perspective: The difference between dancers and controls in the magnitude of variability of pain reports is probably due to the dancers’ extensive training, which focuses on attention to body signals. Our results suggest that training can improve subjective pain reports, which are essential for quality clinical care.
- Is anxiety related to higher vulnerability to a body illusion? Results from the classical rubber hand illusion paradigmPublication . Santos, Duarte; Agostinho, Mariana; Canaipa, Rita
- Mecanismos de dor nas espondiloartrites e a relação com o desempenho cognitivoPublication . Müller, Marlene de Fátima; Canaipa, Rita; Santos, Fernando Manuel Pimentel dosEste estudo teve como objetivo principal investigar a relação entre os mecanismos de dor, através do estudo da resposta do sistema modulador descendente. O estudo foi realizado com o paradigma da Modulação da Dor Condicionada (CPM) e verificada sua relação com o desempenho cognitivo em 17 pacientes, com perturbação da coluna vertebral (espondioartrites), que é um grupo de doenças inflamatórias reumáticas que causam dores, comprometendo a qualidade de vida dos indivíduos. Foi avaliada uma amostra desses doentes, com elevada atividade e repercussão funcional que apresentaram déficits cognitivos e marcada perturbação da qualidade do sono, assim como as vias descendentes da dor (vias inibitórias produtoras de analgesia no cérebro, comprometidas). Esses indivíduos apresentaram sérios problemas físicos e psicológicos e sua saúde mental ficou comprometida, em alguns casos.
- No relationships between the within-subjects' variability of pain intensity reports and variability of other bodily sensations reportsPublication . Agostinho, Mariana; Canaipa, Rita; Honigman, Liat; Treister, RoiPurpose: The subjective nature of pain assessment and its large variance negatively affect patient-health care provider communication and reduce the assay sensitivity of pain clinical trials. Given the lack of an objective gold standard measure, identifying the source (true or error) of the within-subject variability of pain reports is a challenge. By assessing the within-subjects variability of pain and taste reports, alongside with interoceptive measures, the current study is aimed to investigate if the ability to reliably report bodily sensations is a cross-modal characteristic. Patients and Methods: This prospective study enrolled healthy volunteers from local universities. After consenting, subjects underwent the Focus Analgesia Selection Task (FAST), to assess within-subjects variability of pain reports in response to experimental noxious stimuli; a taste task, which similarly assesses within-subjects variability of tastes (salty and sweet) intensity reports; and the heartbeat perception task, an interoceptive task aimed to assess how accurate subjects are in monitoring and reporting their own heartbeat. In addition, all subjects completed the Multidimensional Assessment of Interoceptive Awareness (MAIA), the Perceived Stress Scale (PSS), and Hospital Anxiety and Depression Scale (HADS). Spearman's correlations were used to assess relations between all measures. Results: Sixty healthy volunteers were recruited. Variability of intensity reports of different modalities were independent of each other (P > 0.05 for all correlations). The only correlation found was within modality, between variability of intensity reports of salt and sweet tastes (Spearman's r = 0.477, P < 0.001). No correlations were found between any of the task results and questionnaire results. Conclusion: Within-subjects variability of pain reports do not relate to variability of reports of other modalities or to interoceptive awareness. Further research is ongoing to investigate the clinical relevance of within-subjects' variability of pain reports.
- Relations between short-term memory and the within-subject variability of experimental pain intensity reportsPublication . Canaipa, Rita; Khallouf, Amira; Magalhães, Ana Rita; Teodoro, Rafael; Pão-Mole, Vanessa; Agostinho, Mariana; Pimentel-Santos, Fernando; Honigman, Liat; Treister, RoiWhile factors contributing to between-subjects differences in pain have been studied extensively, factors contributing to the within-subjects variability of pain reports are yet unexplored. The aim of this investigation was to assess possible associations between short-term memory and the within-subjects variability of pain reports in healthy and chronic pain patients. Healthy participants were recruited at the University of Haifa, Israel, and Fibromyalgia patients were recruited at a rheumatology department in a central hospital in Lisbon, Portugal. Following consent, both cohorts underwent the same procedures, including the digit-span test, assessing short-term memory, and the FAST procedure, assessing within-subject variability of pain intensity reports in response to experimental pain. One-hundred twenty-one healthy volunteers and 29 Fibromyalgia patients completed the study. While a significant correlation was found between the within-subjects variability and the total score of the short-term memory task (Spearman’s r = 0.394, P = 0.046) in the Fibromyalgia group, a marginal correlation emerged in the healthy cohort (r = 0.174, P = 0.056). A possible interpretation of these results is that in the patients’ group, at least some of the within-subjects variability of pain intensity reports might be due to error measurement derived by poorer short-term memory, rather than true fluctuations in perception.
- Reliability of the within-subjects variability of pain reports as assessed by the focused analgesia selection test (fast)Publication . Agostinho, Mariana; Shehab, Ons; Hidjazi, Sondos; Canaipa, Rita; Treister, Roi
- Test-retest and interrater reliability of experimental within-subject variability of pain reports as assessed by the focused analgesia selection testPublication . Agostinho, Mariana; Shani, Adi; Canaipa, Rita; Treister, RoiIntroduction: Within-subject variability (WSV) of pain intensity reports has been shown to predict the placebo response. The focused analgesia selection test (FAST), which allows to experimentally assess WSV of pain reports, has been used as a screening tool to identify participants who are likely to have a strong placebo response in drug-development clinical trials. Yet, the reliability of FAST has not been reported. Objectives: To assess test–retest and interrater reliability of the FAST outcomes. To mimic pharma-sponsored clinical trials, we enlisted inexperienced assessors who underwent limited training. Methods: Healthy volunteers performed the FAST twice within a week and were randomly assigned to either the test–retest group or the interrater group. T-tests, partial Pearson correlations, intraclass correlations (ICC), and Bland–Altman plots were generated to assess FAST outcomes’ reliability. Results: Sixty-three participants completed the study and were assigned to the test–retest (N 5 33) or interrater (N 5 30) arms. No statistically significant differences in the FAST outcomes were detected between the 2 sessions, except for the FAST covariance (FAST CoV) in the interrater assessment (P 5 0.009). Test–retest reliabilities of the FAST-main outcomes were r 5 0.461, ICC 5 0.385 for the FAST R2 and r 5 0.605, ICC 5 0.539 for the FAST ICC and in the interrater cohort, they were FAST R2 : r 5 0.321, ICC 5 0.337 and FAST ICC: r 5 0.355, ICC 5 0.330. Conclusion: Using inexperienced assessors, the FAST outcomes test–retest ranged from moderate to strong, whereas the interrater reliability ranged from weak to poor. These results highlight the importance of adequately training study staff members before using this tool in multicentre clinical trials.
- The relationship between the ability to detect ascending sensory signals, and the emotions and beliefs in expectations of pain reduction - an experimental conditioning taskPublication . Agostinho, Mariana; Santos, Duarte; Gutierrez, Adriana Marques Charro; Réfega, Miguel Fernandes; Canaipa, Rita