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Advisor(s)
Abstract(s)
Metabolomics aims at gathering the maximum amount of metabolic information for a total interpretation
of biological systems. A process analytical technology pipeline, combining gas chromatography–mass
spectrometry data preprocessing with multivariate analysis, was applied to a Port wine ‘‘forced ageing’’
process under different oxygen saturation regimes at 60 C.
It was found that extreme ‘‘forced ageing’’ conditions promote the occurrence of undesirable chemical
reactions by production of dioxane and dioxolane isomers, furfural and 5-hydroxymethylfurfural, which
affect the quality of the final product through the degradation of the wine aromatic profile, colour and
taste. Also, were found high kinetical correlations between these key metabolites with benzaldehyde, sotolon,
and many other metabolites that contribute for the final aromatic profile of the Port wine. The use of
the kinetical correlations in time-dependent processes as wine ageing can further contribute to biological
or chemical systems monitoring, new biomarkers discovery and metabolic network investigations.
Description
Keywords
Port wine Forced ageing GC–MS Multivariate analysis Co-expression
Pedagogical Context
Citation
CASTRO, Cristiana C... [et al.] - Application of a high-throughput process analytical technology metabolomics pipeline to Port wine forced ageing process. Food Chemistry. ISSN 0308-8146. Vol. 143 (2014), p. 384–391
Publisher
Elsevier