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O osso de choco tem dois componentes principais, o escudo dorsal e
matriz lamelar, sendo que esta última é constituída essencialmente por
aragonite. A aragonite pode ser convertida hidrotermalmente em fosfatos de
cálcio. Os fosfatos de cálcio são utilizados como materiais de enxerto ósseo ou
adicionados a materiais dentários, por apresentarem semelhança química com
a fase mineral do osso natural e da estrutura dentária. O osso de choco
associado a biovidros favorece as respostas biológicas e aumenta a resistência
deste material.
Este trabalho tem como objetivo avaliar as propriedades antimicrobianas
e citotóxicas de osso de choco associado a biovidros, de forma a selecionar o
material de medicação intra-canalar com maior potencial de aplicação em
endodontia. Protocolos de viabilidade celular e propriedades antimicrobianas
contra Candida albicans, foram elaborados e testados. Foi percetível uma
inibição do crescimento de C. albicans eficaz para a associação osso de choco
e biovidros. Tanto o osso de choco como biovidros registam valores de
viabilidade superiores a 70%.
A aplicação deste tipo de material é promissora na área da endodontia, e
por isso, é necessário aprimorar as propriedades antibacterianas, tendo como
opção a incorporação de iões e a realização de ensaios para Enterococcus
faecalis.
Cuttlefish bone has two main components, the dorsal shield and the lamellar matrix, the latter being essentially made up of aragonite. Aragonite can be hydrothermally converted to calcium phosphates. Calcium phosphates are used as bone graft materials or added to dental materials, as they are chemically similar to the mineral phase of natural bone and tooth structure. The cuttle bone associated with bioglass favors biological responses and increases the resistance of this material. This work aims to evaluate the antimicrobial and cytotoxic properties of cuttle bone associated with bioglass, in order to select the intracanal medication material with the greatest potential for application in endodontics. Cell viability protocols and antimicrobial properties against C. albicans were developed and tested. It was noticeable an inhibition of the growth of C. albicans effective for the association of cuttlefish bone and bioglass. Both cuttle bone and bioglass show viability values above 70%. The application of this type of material is promising in the field of endodontics, and therefore, it is necessary to improve its antibacterial properties, with the option of incorporating ions and carrying out tests for Enterococcus faecalis.
Cuttlefish bone has two main components, the dorsal shield and the lamellar matrix, the latter being essentially made up of aragonite. Aragonite can be hydrothermally converted to calcium phosphates. Calcium phosphates are used as bone graft materials or added to dental materials, as they are chemically similar to the mineral phase of natural bone and tooth structure. The cuttle bone associated with bioglass favors biological responses and increases the resistance of this material. This work aims to evaluate the antimicrobial and cytotoxic properties of cuttle bone associated with bioglass, in order to select the intracanal medication material with the greatest potential for application in endodontics. Cell viability protocols and antimicrobial properties against C. albicans were developed and tested. It was noticeable an inhibition of the growth of C. albicans effective for the association of cuttlefish bone and bioglass. Both cuttle bone and bioglass show viability values above 70%. The application of this type of material is promising in the field of endodontics, and therefore, it is necessary to improve its antibacterial properties, with the option of incorporating ions and carrying out tests for Enterococcus faecalis.
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Palavras-chave
Osso de choco Biovidros Endodontia Medicação intracanalar Citotoxicidade Antimicroabiano Cuttlefish bone Bioglasses Endodontics Intracanal medication Cytotoxicity essays Antimicrobial essays