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Advisor(s)
Abstract(s)
A associação entre a doença periodontal e a doença cardiovascular tem sido alvo de amplos estudos devido à influência de processos inflamatórios na patologia aterosclerótica. Atualmente o conhecimento sobre o papel da doença periodontal como fator de risco para a doença cardiovascular é muito importante numa tentativa de eliminação desse mesmo fator.
Este trabalho é uma análise de alguns estudos epidemiológicos que avaliaram a possibilidade de associação entre estas duas patologias, tendo como objetivo verificar se a patologia periodontal pode ser considerada um fator de risco no desenvolvimento da patologia cardiovascular, a compreensão dos mecanismos desta associação e se a supressão do fator de risco poderá resultar numa diminuição de eventos cardiovasculares. Foram pesquisados artigos em inglês e português, recorrendo a base de dados PubMed, publicados entre 2002 e 2013. Foram utilizados tratados de medicina e medicina dentária como complemento á revisão teórica.
A análise sugere uma possível associação moderada entre a doença periodontal e a doença cardiovascular. Ambas as patologias são de etiologia multidimensional, com diversos fatores de risco em comum e o fato de existirem resultados inconsistentes em diversos estudos indica a impossibilidade de estabelecer uma relação causal. Para que tal aconteça, é necessário a realização de estudos longitudinais bem definidos, segundo classificações de doença periodontal mais específicas assim como um controlo de todos os fatores de confusão
The association between periodontal diseases and cardiovascular diseases has been the target of many studies, due to the influence of inflammatory processes in atherosclerotic pathology. Nowadays the knowledge of periodontal disease has a risk factor to cardiovascular diseases is very important aiming to the elimination of that risk. This work is an analysis of some epidemiological studies that assessed the possible relation between these two diseases, aiming to verify if the periodontal disease may be considered a risk factor for development of cardiovascular diseases, understanding the mechanisms that link them and if the risk factor suppression might result in cardiovascular events decrease. Articles in English and Portuguese, between 2002 and 2013, where researched using the scientific database PubMed. Medicine and dental medicine textbooks were used as a complement to the theoretical review. The analysis suggests a possible moderated association between periodontal and cardiovascular diseases. Both pathologies have multidimensional etiology, common risk factors and the presence of inconsistent results in different studies is indicative of the impossibility to establish a causal relationship. For that to happen it is necessary to accomplish more well defined longitudinal studies, with precise periodontal classification as also the best control of confounding factors.
The association between periodontal diseases and cardiovascular diseases has been the target of many studies, due to the influence of inflammatory processes in atherosclerotic pathology. Nowadays the knowledge of periodontal disease has a risk factor to cardiovascular diseases is very important aiming to the elimination of that risk. This work is an analysis of some epidemiological studies that assessed the possible relation between these two diseases, aiming to verify if the periodontal disease may be considered a risk factor for development of cardiovascular diseases, understanding the mechanisms that link them and if the risk factor suppression might result in cardiovascular events decrease. Articles in English and Portuguese, between 2002 and 2013, where researched using the scientific database PubMed. Medicine and dental medicine textbooks were used as a complement to the theoretical review. The analysis suggests a possible moderated association between periodontal and cardiovascular diseases. Both pathologies have multidimensional etiology, common risk factors and the presence of inconsistent results in different studies is indicative of the impossibility to establish a causal relationship. For that to happen it is necessary to accomplish more well defined longitudinal studies, with precise periodontal classification as also the best control of confounding factors.
Description
Keywords
Doenças periodontais Doenças cardiovasculares Periodontite Aterosclerose Periodontal diseases Cardiovascular diseases Periodontitis Atherosclerosis