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- Detection of the crystallization process of paracetamol with a multi-mode optical fiber in a reflective configurationPublication . Soares, Liliana; Novais, Susana; Ferreira, António; Frazão, Orlando; Silva, SusanaA configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.