Detection of the crystallization process of paracetamol with a multi-mode optical fiber in a reflective configuration

Soares, Liliana; Novais, Susana; Ferreira, António; Frazão, Orlando; Silva, Susana

http://hdl.handle.net/10400.14/29297

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Authors

Soares, Liliana

Novais, Susana

Ferreira, António

Frazão, Orlando

Silva, Susana

Abstract(s)

A configuration of a refractometer sensor is described with the aim of optically detecting the crystallization process of paracetamol. The developed sensing head is based on a conventional cleaved multi-mode fiber. The fiber tip sensor structure was submitted to contact with the liquid of interest (paracetamol fully dissolved in 40% v/v of ethanol/water) and the crystallization process of paracetamol, induced with continued exposure to air, was monitored in real time.

Keywords

Paracetamol Crystallization Multi-mode optical fiber

URI

http://hdl.handle.net/10400.14/29297

Citation

Soares, L., Novais, S., Ferreira, A., Frazão, O., Silva, S. (2020). Detection of the crystallization process of paracetamol with a multi-mode optical fiber in a reflective configuration. Sensors, 20(1), 87