CBQF - Documentos de Conferências / Conference Objects
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- AI-assisted and physics-refined modeling of human voltage-gated sodium channels for selective target discoveryPublication . Boazinha, João Pedro; Carneiro, João; Cerqueira, Nuno M. F. S. A.; Sousa, Sérgio F.Introduction: Voltage-gated sodium channels are membrane proteins that open and close in response to voltage changes to allow Na⁺ influx in excitable cells, enabling action potentials, muscle contraction, and electrical signaling. Aim: Apply a hybrid modelling strategy that combines artificial intelligence and physics-based refinement to build a realistic 3D models of NaV channels.
- Introducing bambara groundnut to the European market: sensory evaluation of a bambara groundnut beveragePublication . Davel, Anissa C.; Vasconcelos, Marta W.; Monteiro, Maria JoãoIntroduction: Bambara Groundnut (BGN), an underutilized African legume, can contribute to food system sustainability due to its genetic diversity, nitrogen-fixing capacity, drought tolerance, and nutritional value. Relatively little attention has been given to BGN added-value processing and product development globally, and in the EU it is a novel commodity. The startup WhatIF Foods (WF) developed a plant-based milk alternative to valorise and create a market for BGN. Objective: Understand whether a BGN beverage is an effective medium to introduce BGN to new consumers in a context where it is unknown. A Portugal-based sensory evaluation was conducted to investigate the product liking and perception compared to market available milk alternatives. This was complemented by a broader online survey investigating consumer response to different BGN product options.
- Introducing legumes into a Portuguese dairy forage system: ecosystem services and practical constraintsPublication . Davel, Anissa Catalina; Iannetta, Pietro; Vasconcelos, MartaIntroduction: The EU depends on a limited number of cereal crops and imported soymeal to meet its feed requirements. Locally produced roughage contributes only 21% to the EU feed protein supply, while home-grown pulses contribute just 2%. There is a need to diversify forage systems and an opportunity to do so with legume-cereal intercrops which are minimally adopted in Europe. Showcasing legume Ecosystem Service (ES) provision can be used as a tool to facilitate adoption, while including farmers in the pilot study research is important for maximising the potential for long-term adoption and subsequent service provision. Objective: Investigate ES provision and adoption potential of different legume mixes against the conventionally used cereal/grass mix on a commercial Northern Portugal dairy farm. How can legumes be introduced into a yield optimised context and what benefits do they provide.
- Balancing performance and context: identifying the right legumes for introduction into a commercial Portuguese dairy farm contextPublication . Davel, Anissa Catalina; Iannetta, Pietro; Vasconcelos, MartaIntroduction: The EU depends on a limited number of cereal crops and imported soymeal to meet its feed requirements. Locally produced roughage contributes only 21% to the EU feed protein supply, while home-grown pulses contribute just 2%. There is a need to diversify forage systems and an opportunity to do so with legume-cereal intercrops which are minimally adopted in Europe. There are a diverse array of legume types which may be used as forage, each with their own potential benefits and challenges. Consequently, co-designing experimental intercrops with farmers is critical to identify best-fit solutions for long-term adoption. Objective and aim: This investigated the codesign process, performance and adoption of legume-based intercrop options relative to conventional cereal/grass mixtures - on a commercial Northern Portugal dairy farm. This aimed to address the research question: How can legume-based intercrops be introduced to optimise yield, and what lessons can we learn to better connect research and practice to maximise impact?
- Method development to investigate consumption habits and flavour preference of Ghanaian children for a bambara groundnut beveragePublication . Davel, Anissa C.; Vasconcelos, Marta W.Improving food quality and access is necessary to combat the prevalence of food insecurity and malnutrition in Sub-Saharan Africa. Bambara Groundnut (BGN), a traditional African legume, can contribute to this. BGN is nutrient dense, nitrogen fixing, and drought tolerant. Consumption of the traditional crop has declined due to cash-crop uptake and BGN’s hard-to-cook factor. The start-up; WhatIF Foods (WF) developed a BGN beverage to valorise BGN, improve livelihoods of small-scale farmers, and combat malnutrition in children. The current landscape is dominated by sweetened milk powders and excess consumption of sweetened beverages. Sugar-free product design is desired, while aligning with local preferences is needed for effective uptake. A sensory evaluation was conducted with children in partner farmer communities (Northern Ghana) to investigate how the BGN beverage should be flavoured.
- Evaluation of stilbenes content in passiflora edulis by-products of the food industryPublication . Krambeck, Karolline; Oliveira, Ana; Santos, Delfim; Pintado, Manuela E.; Silva, João B.; Lobo, José M. S.; Amaral, Maria HelenaIt has been reported that the antioxidant activity of the passion fruit seeds oil is comparable to that of ascorbic acid, due to a high content of polyphenols such as stilbenes. The aim of this study was to use the residues from the Madeira Island food industry to produce passion fruit seed extracts by Soxhlet and Ultrasound methods, using acetone and ethanol, in order to determine the presence of stilbenes (piceatannol and resveratrol) by High-performance liquid chromatography (HPLC). The extracts obtained by the ultrasound method showed high piceatannol and resveratrol content, while the extracts produced by Soxhlet and the commercial oil showed none of these stilbenes. These results suggest that passion fruit oil from Madeira Island can be used by the pharmaceutical and cosmetics industry because of its potential to reduce oxidative stress (ROS).
- Size exclusion flow-based low-pressure chromatographic approach for the molecular weight profiling in protein hydrolysatesPublication . Teixeira, Raquel; Ribas, Tânia C. F.; Almeida, André; Pintado, Manuela; Rangel, António O. S. S.
- Avaliação do gasto energético de repouso do doente crítico: medição direta vs. preditiva ao 3º dia de internamentoPublication . Ferreira, Catarina; Rachão, Bárbara; Silva, Mariana Santos; Cardoso, Fábio; Teixeira, CristinaEnquadramento: A determinação precisa das necessidades energéticas (NE) do doente crítico (DC) é essencial para assegurar o suporte nutricional (SN) adequado [1-3]. A calorimetria indireta (CI) é o método de referência, mas a sua utilização é limitada na prática clínica, sendo substituída por equações preditivas (EP) ou recomendações das sociedades internacionais (RSI) [4-9]. A fiabilidade destas abordagens ao longo do internamento permanece pouco explorada [5,8,10-13]. Objetivo: Avaliar o gasto energético em repouso (GER) do DC através de CI ao 3º dia de internamento e compará-lo com os valores estimados pelas EP e RSI. Métodos: Estudo observacional transversal com 30 doentes internados no Serviço de Medicina Intensiva da Unidade Local de Saúde de São João. As NE foram determinadas por CI, EP (Harris-Benedict, Penn State, Ireton Jones, Swinamer e Faisy) e RSI (ESPEN, ASPEN e BRASPEN), ao 3º dia de internamento. Aplicaram-se testes estatísticos não paramétricos (p<0,05) [5,14-21]. Resultados: A amostra incluiu 63,3% homens, sendo a idade média 62±15 anos (min=23; máx=86), com média de internamento de 23 dias e taxa de mortalidade de 20%. A prevalência de excesso de peso e/ou obesidade foi de 53,3%. A mediana de GER medido por CI foi de 17 kcal/kg (P25=14, P75=20 kcal/kg). Todas as EP e RSI mostraram correlações positivas e estatisticamente significativas (p<0,01) com a CI, destacando-se as EP de Harris-Benedict e Swinamer por apresentarem os coeficientes de correlação mais elevados (rs=0,778). A BRASPEN foi a RSI mais próxima da CI com mediana de 18 kcal/kg (P25=15, P75=25 kcal/kg), p=0,314. A ASPEN subestimou as NE com mediana de 14 kcal/kg (P25=8, P75=16 kcal/kg), p<0,001. As restantes EP e RSI sobrestimaram de forma significativa (p<0,001) as NE. Conclusões: Verificaram-se discrepâncias importantes entre as EP e RSI na estimativa das NE por comparação com a CI, evidenciando a importância da implementação deste método gold standard na prática clínica.
- From legume to latte: innovation and consumer acceptance of a fava bean iced coffeePublication . Osorio, Jazmín; Pinto, Elisabete; Vasconcelos, Marta W.
- Prebiotic potential of oligosaccharides derived from wheat branPublication . Gullón, P.; Gullón, B.; Cardelle-Cobas, A.; Tavaria, F.; Pintado, M. M.; Gomes, A. M.; Alonso, J. L.; Parajó, J. C.As it is well known, the human intestinal microbiota has significant effects on the host health, so that the interest in the maintenance of its balance and activity has fostered the research and development of new prebiotics and probiotics. Non-Digestible Oligosaccharides (NDO) are the most known prebiotics. Oligosaccharides (OS) with prebiotic properties (including inulin, fructooligosaccharides (FOS), galactooligosaccharides (GaOS) and lactulose) are commercially available, and many others are under study. From a nutritional point of view, arabinoxylooligosaccharides (AraXOS) behave as NDO and are classified as “emerging prebiotics” owing to their potential in this field, although strong additional scientific evidence is necessary.