Browsing by Issue Date, starting with "2023-08-02"
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- Understanding economic violence against women: the need for harmonized definitions and data in the EUPublication . European Institute for Gender Equality; Costa, Diogo
- Retórica em ambientes digitaisPublication . Rodrigues, Luís M. FigueiredoO recurso cada vez maior aos dispositivos digitais ligados em rede faz com que surja uma nova cultura: a cultura digital teorizada por Manuel Castells. Está tem um espaço próprio, o ciberes-paço, e disponibilizada um grande acervo de conteúdos, criando aquilo que Pierre Lévy chama inteligência coletiva. Embora se alicerce sobre a crença tecnocrática de que a tecnologia promove o progresso humano, algumas pesquisas demonstram que as reais utilizações estão aquém do desejado e teorizado. As análises que se realizaram em Portugal sobre o uso da Web por parte da Igreja católica, no prosseguimento da sua missão, comprovam precisamente isso. São várias as hipóteses que procuram explicar o fenómeno. Neste texto procura-se demonstrar que uma das fragilidades existentes é que as diversas análises não consideraram a necessidade de uma nova retórica, a retórica digital.
- Assessing the in vitro digestion of lactoferrin-curcumin nanoparticles using the realistic gastric modelPublication . Madalena, Daniel A.; Araújo, João F.; Ramos, Óscar L.; Vicente, António A.; Pinheiro, Ana C.Nanosized delivery systems have been the subject of research and discussion in the scientific community due to their unique properties and functionality. However, studies reporting the behaviour of nanodelivery systems under dynamic in vitro digestion conditions are still very scarce. To address this gap, this study aims to assess the dynamic in vitro gastric digestion of lactoferrin/curcumin nanoparticles in the realistic gastric model (RGM). For this purpose, the INFOGEST standard semi-dynamic digestion protocol was used. The nanosystems were characterized in terms of hydrodynamic size, size distribution, polydispersity index (PdI), and zeta potential using dynamic light scattering (DLS), before and during the digestion process. Confocal laser scanning microscopy (CLSM) was also used to examine particle aggregation. In addition, the release of curcumin was evaluated spectroscopically and the intrinsic fluorescence of lactoferrin was measured throughout the digestion process. The protein hydrolysis was also determined by UV-VIS-SWNIR spectroscopy to estimate, in real-time, the presence of free NH2 groups during gastric digestion. It was possible to observe that lactoferrin/curcumin nanoparticles were destabilized during the dynamic digestion process. It was also possible to conclude that low sample volumes can pose a major challenge in the application of dynamic in vitro digestion models.
- Editorial: urban nature-based solutions and green infrastructure as strategies for climate change adaptationPublication . Matos, Cristina; Monteiro, Cristina M.; Santos, Cristina; Briga-Sá, Ana; Imteaz, Monzur Alam
- Understanding psychological violence against women: the need for harmonized definitions and data in the EUPublication . European Institute for Gender Equality; Costa, Diogo