Browsing by Author "Alves, Paula"
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- Acute hospitalization of cancer community-based patients: a cross sectional look into identifying nutritional risk, status and functional compromise and a window onto nutritional perceptions and unmet needsPublication . Neto, Elisabete; Alves, Paula; Correia, Marta; Irving, SusanaBackground - Cancer-related malnutrition is prevalent. Moreover, nutritional status can be dynamic, resulting from a cumulative risk of deterioration, specially if multimodal treatments are proposed. Nowadays, due to treatment advances, more people living with cancer are being managed as community-based outpatients. Systematic nutritional risk identification should be conducted and established throughout the oncology care continuum. Objectives - To evaluate the nutritional risk and status, and functional compromise of cancer patients at an acute hospitalization timepoint. to capture participant’s nutritional perceptions and unmet needs whilst outpatients
- Correction: IgG antibodies to SARS-CoV-2 in asymptomatic blood donors at two time points in KarachiPublication . Hasan, Muhammad; Moiz, Bushra; Qaiser, Shama; Masood, Kiran Iqbal; Ghous, Zara; Hussain, Areeba; Ali, Natasha; Simas, J. Pedro; Veldhoen, Marc; Alves, Paula; Abidi, Syed Hani; Ghias, Kulsoom; Khan, Erum; Hasan, Zahra
- Evolução nutricional em doentes oncológicos submetidos a colocação de prótese esofágica: estudo retrospectivoPublication . Torres, Cláudia; Alves, Paula; Pinto, ElisabeteIntroduction: The esophageal stent placement is an effective procedure to restore the intake “per os” in patients with esophageal obstruction. Objectives: To describe, retrospectively, the evolution of nutritional intake, symptoms associated with food intake and anthropometry of all the patients submitted to an esophageal stent placement in IPOFG, EPE, between January 2009 and December 2010, for which the main diagnosis was esophageal or gastric cancer. Methodology: Observational descriptive study of 98 patients. We assessed the nutritional and dietary records in medical files of cancer patients with esophageal stent placement in the study period. Data were collected with a standardized protocol. Results: The most (75,5%) of participants were men and 57,1% were older than 60 years, with women being significantly older. The main diagnosis for 76,5% of patients was esophageal cancer. Regarding the symptoms prior to placement of the stent, almost all patients (n = 90) had dysphagia, and for 49,5% was dysphagia to solids. Regarding the type of the stent, 63,3% of patients received a non-covered self-expanding metal stent. The median time between diagnosis and death was 354,0 days and between the placement of the first stent and the death was 124,5 days. Comparing the usual weight with the weight near the stent placement, patients lost a median of 16kg (P25;P75: 12,5;24,0). Conclusions: These cancers are associated with significant weight losses, partly due to dysphagia. As a retrospective study, being in account the number of nutrition assessments available after stent placement, it was not possible to objectively measure the benefit of the stent placement regarding the nutritional status. However, the purpose of allowing oral feeding was certainly achieved, indeed highly valued by patients.
- (In)sucesso escolar: a influência das estratégias de estudo e aprendizagemPublication . Ribeiro, Célia; Alves, PaulaO insucesso escolar continua a afectar muitos dos nossos alunos. A identificação das causas e das formas de o colmatar é uma preocupação que vem sendo partilhada já há muitos anos por investigadores educacionais, por professores e pelos órgãos de gestão das escolas. A literatura consultada sobre esta temática levou-nos ao conhecimento sobre a existência de vários factores, intrínsecos e extrínsecos aos alunos, responsáveis pelo (in) sucesso escolar e ao reconhecimento de que não há uma forma única e ideal de ensinar e de aprender. Assim, o presente artigo incide sobre as estratégias de estudo e aprendizagem, considerando-as como um dos possíveis factores que influenciam o (in) sucesso escolar.
- The influence of diet and obesity in Lynch syndrome: what do we know so farPublication . Rodrigues, Cláudio; Irving, Susana Couto; Alves, Paula; Dinis-Ribeiro, Mário; Brandão, Catarina; Correia, MartaOf all new cases of colorectal cancer, Lynch syndrome (LS) accounts for approximately 3%. This syndrome is the most common hereditary cancer syndrome and is caused by pathogenic variants in the genes responsible for DNA mismatch repair. Although the relationship between colorectal cancer risk and diet is well established, little is known regarding the influence of diet and nutritional characteristics on LS’s clinical evolution. There is some evidence suggesting that individuals living with LS should follow general guidelines for diet and alcohol restriction/moderation, so as to achieve and maintain a favorable weight status and overall health and quality of life. However, more research is needed, preferentially from clinical studies of a prospective nature with robust designs, to better inform diet and behavioral patterns targeting cancer prevention in LS.
- What is new in cancer cachexia comprehension and treatment?Publication . Dias, Mariana; Irving, Susana; Alves, Paula; Correia, MartaCancer cachexia is a multifactorial syndrome, associated with an underlying illness, characterized by involuntary weight loss and skeleton muscle mass impairment and reduction, with or without loss of fat mass. It emerges within a systemic inflammation and metabolic disturbance setting, entailing a significant impact in treatment toxicity, quality of life, functional capacity and mortality. Although the conventional nutritional support includes symptom management, inflammation and metabolic modulation and treatment effectiveness, it is not able to fully revert cancer cachexia. The nutritional goals are to provide adequate energy and protein intake along with a combination of anti-inflammatory agents and other nutrients. In this review we focus on the effect of certain nutrients and bioactive molecules in muscle loss, inflammation and cancer cachexia (β-hydroxy-β-methyl butyrate, branched chain amino acids, polyunsaturated fatty acids, carnitine, polyphenols and vitamin D). Food sources providing the later nutrients/molecules should be endorsed, in addition to a conventional nutritional support, as it is expected to entail specific functions in cancer cachexia.