Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.14/2703
Título: Determination of antioxidant capacity using the biological system bacteriophage P22/bacterium salmonella typhimurium
Autor: Gião, Maria S.
Borges, André B.
Guedes, Catarina J.
Hogg, Tim A.
Pintado, Manuela E.
Malcata, F. Xavier
Palavras-chave: Ascorbic acid
Gallic acid
In vivo assessment
Data: 2009
Editora: American Chemical Society
Citação: "Journal of Agriculture and Food Chemistry". ISSN 1520-5118. 57:1 (2009) 22-25
Resumo: Bacteriophage/bacterium systems have been employed in the past in assays for virucidal activity. A novel application of one such system is proposed here for the in vivo determination of antioxidant capacity. It was shown that an antioxidant such as gallic acid can effectively protect against oxidative damage brought about by H2O2sbut only within a narrow range of concentrations (i.e., from 250 to 500 mg L-1); ascorbic acid, on the other hand, did not exhibit any protective effect against H2O2. Finally, neither ascorbic nor gallic acid demonstrated a virucidal effect. The P22/Salmonella typhimurium model system thus proved to be useful in the assessment of antioxidant capacity in vivo, at least using those two alternative model antioxidants.
URI: http://hdl.handle.net/10400.14/2703
Versão do Editor: http://pubs.acs.org/doi/abs/10.1021/jf802185k
Aparece nas colecções:ESB - Artigos em revistas internacionais com Arbitragem / Papers in international journals with Peer-review

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