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Determination of antioxidant capacity using the biological system bacteriophage P22/bacterium salmonella typhimurium

2009Journal article Restricted access
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dc.contributor.authorGião, Maria S.
dc.contributor.authorBorges, André B.
dc.contributor.authorGuedes, Catarina J.
dc.contributor.authorHogg, Tim
dc.contributor.authorPintado, Manuela E.
dc.contributor.authorMalcata, F. Xavier
dc.date.accessioned2010-10-08T10:17:21Z
dc.date.available2010-10-08T10:17:21Z
dc.date.issued2009
dc.description.abstractBacteriophage/bacterium systems have been employed in the past in assays for virucidal activity. A novel application of one such system is proposed here for the in vivo determination of antioxidant capacity. It was shown that an antioxidant such as gallic acid can effectively protect against oxidative damage brought about by H2O2sbut only within a narrow range of concentrations (i.e., from 250 to 500 mg L-1); ascorbic acid, on the other hand, did not exhibit any protective effect against H2O2. Finally, neither ascorbic nor gallic acid demonstrated a virucidal effect. The P22/Salmonella typhimurium model system thus proved to be useful in the assessment of antioxidant capacity in vivo, at least using those two alternative model antioxidants.por
dc.identifier.doi10.1021/jf802185k
dc.identifier.eid59849083574
dc.identifier.pmid19072632
dc.identifier.urihttp://hdl.handle.net/10400.14/2703
dc.identifier.wos000262292700002
dc.language.isoengpor
dc.publisherAmerican Chemical Societypor
dc.subjectAscorbic acidpor
dc.subjectGallic acidpor
dc.subjectIn vivo assessmentpor
dc.titleDetermination of antioxidant capacity using the biological system bacteriophage P22/bacterium salmonella typhimuriumpor
dc.typejournal article
dspace.entity.typePublication
person.familyNameHogg
person.familyNamePintado
person.familyNameMalcata
person.givenNameTim
person.givenNameMaria Manuela
person.givenNameFrancisco
person.identifier456608
person.identifier.ciencia-idFF11-88CC-8BD4
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.ciencia-id1B13-38A5-35F5
person.identifier.orcid0000-0003-2017-4131
person.identifier.orcid0000-0002-0760-3184
person.identifier.orcid0000-0003-3073-1659
person.identifier.ridJXY-0365-2024
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id7005603860
person.identifier.scopus-author-id7004483898
person.identifier.scopus-author-id7102542478
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication12b8092d-fe59-408b-8058-47369a97d229
relation.isAuthorOfPublicationba387c7d-27c9-4016-895c-b35597e91ebc
relation.isAuthorOfPublicationa06c00da-0e2f-4434-8ede-4d7b22c0dfe9
relation.isAuthorOfPublication.latestForDiscovery12b8092d-fe59-408b-8058-47369a97d229

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