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Resumo(s)
A incidência global de cancro, particularmente cancro da cama, tem vindo a aumentar nas últimas décadas, com a cavidade oral a ser um dos locais afectados por efeitos adversos, nomeadamente osteoquimionecrose, devido ao uso de fármacos como os bifosfonatos e mais recentemente anticorpos monoclonais.
Objectivos: Analisar e caracterizar as complicações orais associadas ao tratamento oncológico em doentes com neoplasia da mama.
Materiais e Métodos: Um estudo observacional retrospectivo foi realizado. Os registos clínicos de 32 pacientes a receberem quimioterapia e radioterapia no Hospital Santos Silva(Centro Hospitalar de Vila Nova de Gaia /Espinho). De seguida todos os pacientes serão submetidos a examinação intra-oral e a um questionário. Tipo de Tumor, Estadio Tumoral , Esquemas Terapeuticos e manifestações orais serão determinados e a análise estatistica realizada usando SPSS 21.0.
Resultados : Foi obtida uma amostra de 32 pacientes, Carcinomas Invasivos foram os mais observados com uma incidência de 56.25% (n=18). Estadio IIIA foi o mais comum entre os vários estadios observados com uma incidência de 25% (n=8). FEC, 46.9% (n=15), foi o esquema terapêutico de quimioterapia mais utilizado. Disgeusia foi a manifestação oral mais frequente com uma incidência de 81.3%.
Conclusão: O conhecimento deste tipo de complicações decorrentes do tratamento do cancro da mama por parte dos pacientes é bastante reduzido e desvalorizadas pelos mesmos. É da nossa opinião que mais estudos sobre a ocorrência destas complicações durante o tratamento oncológico sejam realizados pelas entidades competentes de modo a permitirem o aumento da qualidade de vida do doente oncológico
The overall incidence of cancer, particularly breast cancer, has increased substantially over the last decades, with the oral cavity being one of the locations where side effects usually occur, namely osteochemonecrosis, as a consequence of the use of drugs such as bisphosphonates and, more recently, monoclonal antibodies. Purpose: To analyse and further characterise the main oral manifestations of cancer treatment associated with patients with breast neoplasm. Material and methods: A retrospective observational study as carried out. Records from 32 patients undergoing chemotherapy will be retrieved from the Hospital Santos Silva (CHVNG/E) files and reviewed. Patients will subsequently be observed and a questionnaire applied. Tumour type, stage, therapeutic regimens, and oral manifestations will be determined and a statistical analysis performed using SPSS 21.0. Results: A sample of 32 patients was obtained. Invasive Carcinoma were the most common breast neoplasm form with an incidence of 56.25% (n=18). Stage IIA was the most common with an incidence of 25 % (n=8). FEC, 46.9% (n=15), was the most employed therapeutic chemotherapy regimens. Dysgeusia was the most common oral complication observed with an incidence of 81.3% (n=26) Conclusion: The awareness for oral complications during breast neoplasm between patients is very low and undervalued by them. More study on the subject are necessary so that the quality of life for the oncological patient can be improved significantly.
The overall incidence of cancer, particularly breast cancer, has increased substantially over the last decades, with the oral cavity being one of the locations where side effects usually occur, namely osteochemonecrosis, as a consequence of the use of drugs such as bisphosphonates and, more recently, monoclonal antibodies. Purpose: To analyse and further characterise the main oral manifestations of cancer treatment associated with patients with breast neoplasm. Material and methods: A retrospective observational study as carried out. Records from 32 patients undergoing chemotherapy will be retrieved from the Hospital Santos Silva (CHVNG/E) files and reviewed. Patients will subsequently be observed and a questionnaire applied. Tumour type, stage, therapeutic regimens, and oral manifestations will be determined and a statistical analysis performed using SPSS 21.0. Results: A sample of 32 patients was obtained. Invasive Carcinoma were the most common breast neoplasm form with an incidence of 56.25% (n=18). Stage IIA was the most common with an incidence of 25 % (n=8). FEC, 46.9% (n=15), was the most employed therapeutic chemotherapy regimens. Dysgeusia was the most common oral complication observed with an incidence of 81.3% (n=26) Conclusion: The awareness for oral complications during breast neoplasm between patients is very low and undervalued by them. More study on the subject are necessary so that the quality of life for the oncological patient can be improved significantly.
Descrição
Palavras-chave
Complicações Orais Mama Neoplasia Cancro Terapia Xerostomia Quimioterapia Radioterapia Mucosite Complications Oral Breast neoplasm Cancer therapy Chemotherapy Radiotherapy Mucositis