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Fecal microbiota transplantation in the intestinal decolonization of carbapenamase-producing enterobacteriaceae

2020Journal article Open access
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dc.contributor.authorSilva, João Carlos
dc.contributor.authorPonte, Ana
dc.contributor.authorMota, Margarida
dc.contributor.authorPinho, Rolando
dc.contributor.authorVieira, Nuno
dc.contributor.authorOliveira, Rosa
dc.contributor.authorMota-Carvalho, Nelson
dc.contributor.authorGomes, Ana Catarina
dc.contributor.authorAfecto, Edgar
dc.contributor.authorCarvalho, João
dc.date.accessioned2021-01-29T11:46:45Z
dc.date.available2021-01-29T11:46:45Z
dc.date.issued2020
dc.description.abstractBackground and aims: fecal microbiota transplantation (FMT) is effective for recurrent Clostridium difficile infection (CDI). Intestinal decolonization of carbapenamase-producing enterobacteriaceae (CPE) can prevent transmission and infection by these agents. The aim of this study was to assess CPE decolonization after FMT. Methods: this was a case-series study that consecutively included all CPE-carriers that underwent FMT between 2014 and 2019. The indications included refractory/recurrent CDI and CPE-decolonization. Results: out of 21 CPE-carriers, eight were excluded due to incomplete post-FMT testing. CPE decolonization was confirmed in 76.9 % (n = 10). The median decolonization time was 16-weeks (IQR-23) and ranged from two to 53 weeks. Conclusion: FMT may be used in the clinical practice for CPE-decolonization as an alternative to combined antibiotic regimens.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSilva, J. C., Ponte, A., Mota, M., Pinho, R., Vieira, N., Oliveira, R., ... Edgar, A. (2020). Fecal microbiota transplantation in the intestinal decolonization of carbapenamase-producing enterobacteriaceae. Revista Espanola de Enfermedades Digestivas, 112(12), 925-928pt_PT
dc.identifier.doi10.17235/reed.2020.7150/2020pt_PT
dc.identifier.eid85096328785
dc.identifier.eissn2340-4167
dc.identifier.issn1130-0108
dc.identifier.pmid33118360
dc.identifier.urihttp://hdl.handle.net/10400.14/31815
dc.identifier.wos000597214000006
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedad Española de Patología Digestivapt_PT
dc.subjectFecal microbiota transplantationpt_PT
dc.subjectCarbapenamase-producing enterobacteriaceaept_PT
dc.subjectMultidrug-resistant infectionspt_PT
dc.subjectDecolonizationpt_PT
dc.subjectIntestinal carriagept_PT
dc.titleFecal microbiota transplantation in the intestinal decolonization of carbapenamase-producing enterobacteriaceaept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage928pt_PT
oaire.citation.issue12pt_PT
oaire.citation.startPage925pt_PT
oaire.citation.titleRevista Espanola de Enfermedades Digestivaspt_PT
oaire.citation.volume112pt_PT
person.familyNamePinho
person.familyNameMota de Carvalho
person.givenNameRolando
person.givenNameNelson
person.identifier.ciencia-idA01E-3E9A-6F9B
person.identifier.orcid0000-0002-2208-8408
person.identifier.orcid0000-0002-8691-8255
person.identifier.scopus-author-id24077067800
person.identifier.scopus-author-id57208901256
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication8a72172b-ecf3-4424-92fe-0b0dc0ba5603
relation.isAuthorOfPublicationd7e4413a-6a51-490c-879b-ac6c64b55ad7
relation.isAuthorOfPublication.latestForDiscoveryd7e4413a-6a51-490c-879b-ac6c64b55ad7

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