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Oral mucositis management in children under cancer treatment: a systematic review

2024-04-18Journal article Open access
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dc.contributor.authorBraguês, Ricardo
dc.contributor.authorMarvão, Maria Francisca
dc.contributor.authorCorreia, Patrícia
dc.contributor.authorSilva, Raquel M.
dc.date.accessioned2024-05-07T15:18:35Z
dc.date.available2024-05-07T15:18:35Z
dc.date.issued2024-04-18
dc.description.abstractChildren undergoing antineoplastic treatment often present severe side effects due to the dosage and duration of treatments, with oral mucositis emerging as one of the most prevalent and painful inflammatory conditions. There is a growing body of evidence on therapeutic interventions such as cryotherapy, low-level laser therapy, and natural compounds for this condition. The aim of this systematic review was to identify and compare therapies for the management of cancer treatment-induced oral mucositis in pediatric patients. From 2655 articles obtained in initial searches, 39 articles were considered in this systematic review, after applying inclusion/exclusion criteria. Low-level laser therapy, palifermin, honey, and zinc demonstrated reductions in oral mucositis incidence, duration, severity, and pain reported by the patient. Although there are several therapies in place for the prevention and treatment of oral mucositis in children, evidence of their efficacy is still inconclusive to establish accurate clinical protocols.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/cancers16081548pt_PT
dc.identifier.eid85191411405
dc.identifier.issn2072-6694
dc.identifier.pmcPMC11048343
dc.identifier.pmid38672630
dc.identifier.urihttp://hdl.handle.net/10400.14/44936
dc.identifier.wos001210189400001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCalcium phosphatept_PT
dc.subjectHoneypt_PT
dc.subjectLow-level laser therapypt_PT
dc.subjectOral mucositispt_PT
dc.subjectPaliferminpt_PT
dc.subjectPediatric cancerpt_PT
dc.subjectPreventionpt_PT
dc.subjectTherapeuticspt_PT
dc.subjectZincpt_PT
dc.titleOral mucositis management in children under cancer treatment: a systematic reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue8pt_PT
oaire.citation.titleCancerspt_PT
oaire.citation.volume16pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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