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Abstract(s)
O aumento da incidência dos tumores da cabeça e pescoço tem sido verificada ao longo do tempo. A necessidade de efectuar estudos científicos que tenham em vista a caracterização dos tumores, nomeadamente, a sua incidência, localização, evolução, agressividade e o potencial de resposta ao tratamento sistémico com ou sem radioterapia, é reconhecida.
Neste trabalho procedeu-se à realização de um estudo epidemiológico observacional e retrospectivo onde foram recolhidos dados relativos a 96 doentes, 55,2% do sexo feminino com uma idade média de diagnóstico de 54,1%±18,9 anos.
Entre os objectivos do estudo estão a avaliação do comportamento clínico e patológico dos tumores das glândulas salivares major, a correlação entre o diagnóstico (resultado anátomo-patológico) e a terapêutica instituída com o respectivo prognóstico e resultado final.
A entidade anátomo-patológica mais comum, presente em 45% dos casos analisados, foi o adenoma pleomórfico e o tumor maligno mais comum na amostra foi o carcinoma espinho celular (8%). Os locais preferenciais de metastização foram a ganglionar e pulmonar, nos estádios III e IV. A maioria dos doentes encontra-se em controlo clínico (88%), verificando-se 11 falecimentos (12%).
The increased incidence of head and neck tumors has been observed over some time. The need for scientific studies that are based on characterization of the tumors, the incidence, location, evolution, aggressiveness and potential response to systemic treatment with or without radiotherapy, have to be widely performed. In this work it was made an observational and retrospective epidemiological study in witch was collected data on 96 patients, 55.2% female with an average age at diagnosis of 54.1% ± 18.9 years. Among the objectives of the study there is the evaluation of the clinical and pathological behavior of major salivary gland tumors, the correlation diagnosis (pathological findings) and treatment instituted with their prognosis and outcome. The most common pathologic entity, with 45% of the cases analyzed, was the pleomorphic adenoma and the most common malignancy in the sample cell carcinoma was the thorn (8%). The preferred sites of metastasis were the lung and lymph nodes in stages III and IV. Most patients are in clinical management (88%) and there were 11 deaths (12%).
The increased incidence of head and neck tumors has been observed over some time. The need for scientific studies that are based on characterization of the tumors, the incidence, location, evolution, aggressiveness and potential response to systemic treatment with or without radiotherapy, have to be widely performed. In this work it was made an observational and retrospective epidemiological study in witch was collected data on 96 patients, 55.2% female with an average age at diagnosis of 54.1% ± 18.9 years. Among the objectives of the study there is the evaluation of the clinical and pathological behavior of major salivary gland tumors, the correlation diagnosis (pathological findings) and treatment instituted with their prognosis and outcome. The most common pathologic entity, with 45% of the cases analyzed, was the pleomorphic adenoma and the most common malignancy in the sample cell carcinoma was the thorn (8%). The preferred sites of metastasis were the lung and lymph nodes in stages III and IV. Most patients are in clinical management (88%) and there were 11 deaths (12%).
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Keywords
Tumores Glândulas salivares major Classificação TNM Metastização Envolvimento perineural Tumors Major salivary glands TNM classification Metastasis Perineural, involvement