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Biodentine for furcation perforation repair: an animal study with histological, radiographic and micro-computed tomographic assessment

2018-06-01Journal article Open access
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dc.contributor.authorCardoso, Miguel
dc.contributor.authorPires, Maria dos Anjos
dc.contributor.authorCorrelo, Vitor
dc.contributor.authorReis, Rui
dc.contributor.authorPaulo, Manuel
dc.contributor.authorViegas, Carlos
dc.date.accessioned2021-05-13T13:35:56Z
dc.date.available2021-05-13T13:35:56Z
dc.date.issued2018-06-01
dc.description.abstractIntroduction: Biodentine has been scarcely studied as a furcation perforation (FP) repair material, mostly by in vitro methodologies. This animal study aimed to compare the histological responses, radiographic, and micro-computed tomographic (micro-CT) outcomes after FP repair with Biodentine or ProRoot MTA (MTA) in dogs’ teeth. Methods and Materials: Fifty teeth from five dogs were divided into 4 groups: MTA (n=20, FP repaired with ProRoot MTA), BDT (n=20, FP repaired with Biodentine), PC (n=5, positive control, FP without repair) and NC (n=5, negative control, without perforation). The animals were euthanized after 4 months. Histological assessment included inflammatory cell infiltration, hard tissue resorption, hard tissue repair, and cement repair in the furcation area. Immediate postoperative and 4 months follow-up radiographs were compared for radiolucency in the furcation region. The volume of extruded material was quantified using micro-CT images. Results: The tested materials showed equivalent radiographic response, together with similar hard tissue resorption and repair but, BDT group showed significantly less inflammation, lower volume of extruded material and higher cement repair than MTA group. Conclusion: The outcomes of this study, taken together with other favorable results in literature, are highly suggestive that Biodentine is a promising biomaterial to be used for FP repair.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.22037/iej.v13i3.19890pt_PT
dc.identifier.eid85049905610
dc.identifier.issn1735-7497
dc.identifier.urihttp://hdl.handle.net/10400.14/33088
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectBiodentinept_PT
dc.subjectBiomaterialpt_PT
dc.subjectEndodonticspt_PT
dc.subjectFurcation perforationpt_PT
dc.subjectImagingpt_PT
dc.subjectMicro-computed tomographypt_PT
dc.titleBiodentine for furcation perforation repair: an animal study with histological, radiographic and micro-computed tomographic assessmentpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage330pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPage323pt_PT
oaire.citation.titleIranian Endodontic Journalpt_PT
oaire.citation.volume13pt_PT
person.familyNameCardoso
person.familyNameCorrelo da Silva
person.familyNameReis
person.familyNameViegas
person.givenNameMiguel
person.givenNameVitor Manuel
person.givenNameRui L.
person.givenNameCarlos
person.identifier832165
person.identifier186286
person.identifier.ciencia-id0313-CA28-4702
person.identifier.ciencia-id511F-4C03-9F61
person.identifier.ciencia-id6F11-C02E-8B6C
person.identifier.ciencia-id4519-B7D7-08ED
person.identifier.orcid0000-0003-2916-0537
person.identifier.orcid0000-0002-5516-7583
person.identifier.orcid0000-0002-4295-6129
person.identifier.orcid0000-0002-8796-5037
person.identifier.ridO-4227-2015
person.identifier.ridA-8938-2008
person.identifier.ridD-2207-2014
person.identifier.scopus-author-id57194223030
person.identifier.scopus-author-id10739145300
person.identifier.scopus-author-id56861715700
person.identifier.scopus-author-id6701584816
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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