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The burden of atherosclerosis in Portugal

2021-03-15Journal article Open access
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dc.contributor.authorCosta, João
dc.contributor.authorAlarcão, Joana
dc.contributor.authorAraujo, Francisco
dc.contributor.authorAscenção, Raquel
dc.contributor.authorCaldeira, Daniel
dc.contributor.authorFiorentino, Francesca
dc.contributor.authorGil, Victor
dc.contributor.authorGouveia, Miguel
dc.contributor.authorLourenço, Francisco
dc.contributor.authorSilva, Alberto Mello E
dc.contributor.authorSampaio, Filipa
dc.contributor.authorCarneiro, António Vaz
dc.contributor.authorBorges, Margarida
dc.date.accessioned2021-03-31T13:15:39Z
dc.date.available2021-03-31T13:15:39Z
dc.date.issued2021-03-15
dc.description.abstractAIMS: This article sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016. METHODS AND RESULTS: The burden of atherosclerosis was measured in disability-adjusted life years following the latest 2010 Global Burden of Disease (GBD) methodology. Disability-adjusted life years were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clinical manifestations of atherosclerosis were included: ischaemic heart disease (IHD) (including acute myocardial infarction, stable angina, and ischaemic heart failure), ischaemic cerebrovascular disease (ICVD), and peripheral arterial disease (PAD). Years of life lost were estimated based on all-cause mortality data for the Portuguese population and mortality due to IHD, ICVD, and PAD for the year 2016 sourced from national statistics. Standard life expectancy was sourced from the GBD study. Years lived with disability corresponded to the product of the number of prevalent cases by an average disability weight for all possible combinations of disease. Prevalence data for the different clinical manifestations of atherosclerosis were sourced from epidemiological studies. Disability weights were sourced from the published literature. In 2016, 15 123 deaths were attributable to atherosclerosis, which corresponded to 14.3% of overall mortality in mainland Portugal. Disability-adjusted life years totalled 260 943, 75% due to premature death (196 438 YLL) and 25% due to disability (64 505 YLD). CONCLUSION: Atherosclerosis entails a high disease burden to society. A large part of this burden would be avoidable if evidence-based effective and cost-effective interventions targeting known risk factors, from prevention to treatment, were implemented.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1093/ehjqcco/qcaa060pt_PT
dc.identifier.eid85102965227
dc.identifier.issn2058-5225
dc.identifier.pmcPMC7962771
dc.identifier.pmid32946553
dc.identifier.urihttp://hdl.handle.net/10400.14/32420
dc.identifier.wos000637042000008
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAtherosclerosispt_PT
dc.subjectBurden of diseasept_PT
dc.subjectDALYspt_PT
dc.subjectMorbiditypt_PT
dc.subjectMortalitypt_PT
dc.subjectPortugalpt_PT
dc.titleThe burden of atherosclerosis in Portugalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage162pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage154pt_PT
oaire.citation.titleEuropean heart journal. Quality of care & clinical outcomespt_PT
oaire.citation.volume7pt_PT
person.familyNameCosta
person.familyNameAraújo
person.familyNameCaldeira
person.familyNameGil
person.familyNameGouveia
person.familyNameSampaio
person.familyNameBorges
person.givenNameJoão
person.givenNameFrancisco
person.givenNameDaniel
person.givenNameVictor
person.givenNameMiguel
person.givenNameFilipa
person.givenNameMargarida
person.identifier480560
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person.identifier.orcid0000-0002-5831-4921
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person.identifier.orcid0000-0002-2520-5673
person.identifier.orcid0000-0003-4014-5450
person.identifier.orcid0000-0003-0081-0508
person.identifier.orcid0000-0002-5540-9853
person.identifier.orcid0000-0002-8563-6846
person.identifier.ridQ-2095-2015
person.identifier.scopus-author-id55499748300
person.identifier.scopus-author-id35515214000
person.identifier.scopus-author-id36623384200
person.identifier.scopus-author-id57201233134
person.identifier.scopus-author-id7003491970
person.identifier.scopus-author-id7102828573
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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