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Introdução/enquadramento/objetivos: O cancro do pĆ¢ncreas apresenta elevada letalidade. Parte da sua etiologia poderĆ” associar-se Ć atividade laboral, pelo que o conhecimento dos fatores de risco em ambiente de trabalho serĆ” importante para o desempenho das equipas de SaĆŗde e SeguranƧa ocupacionais. Assim, tendo em conta que a evidĆŖncia sobre o assunto Ć© escassa, pretendeu-se com esta revisĆ£o sintetizar a informação disponĆvel e mais atual sobre o tema. Metodologia: O estudo de RevisĆ£o BibliogrĆ”fica, teve origem numa pesquisa realizada em janeiro de 2022, nas bases de dados āCINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina e RCAAPā. ConteĆŗdo: Em 2008 estimaram-se cerca de 280.000 novos casos, mundialmente. Devido Ć baixa taxa de sobrevivĆŖncia, o nĆŗmero de incidĆŖncia Ć©, a mĆ©dio prazo, parecido ao da mortalidade. A taxa de sobrevivĆŖncia a cinco anos em alguns paĆses Ć© de 7 e 8% para os sexos masculino e feminino, respetivamente. Esta patologia geralmente nĆ£o apresenta resultados encorajadores em relação Ć quimioterapia ou radioterapia. Ainda que sem consenso total, acredita-se que o sexo masculino seja atingido com maior probabilidade. DiscussĆ£o e ConclusƵes: Parte dos cancros pancreĆ”ticos poderĆ” ter origem ocupacional atravĆ©s do contato com radiação ionizante e sobretudo alguns agentes quĆmicos: pesticidas, fertilizantes, cĆ”dmio, nĆquel (e outros metais pesados), nitrosaminas, hidrocarbonetos clorinados e aromĆ”ticos policĆclicos, sĆlica/asbestos, fluidos da metalurgia, tintas e fumos diesel. Assim, os setores profissionais mais relevantes serĆ£o a agricultura e jardinagem, limpeza a seco, construção civil/naval (e Ć”reas afins), bem como fotografia. Tendo em conta a escassez de dados a nĆvel nacional, seria relevante obter estudos que explorassem este fenómeno, nomeadamente, quais os nĆveis de exposição a fatores de risco, potencialmente cancerĆgenos, quais as profissƵes mais atingidas, que medidas de proteção foram equacionadas, bem como a sua efetividade ou, atĆ© mesmo, a taxa de retorno laboral e suas eventuais limitaƧƵes.
Introduction/framework/objectives: Pancreatic cancer has a high mortality rate. Part of the etiology, for some researchers, may be related to work activities, so knowledge of risk factors may be important for the performance of Occupational Health and Security teams. Thus, taking into account that the evidence on the subject is scarce, the aim of this review was to summarize the available and most current information. Methodology: This is a Bibliographic Review, initiated through a search carried out in January 2022 in the databases āCINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAPā. Content: In 2008, around 280,000 new cases were estimated worldwide. Due to the low survival rate, the incidence number is similar to the mortality rate in the medium term. The five-year survival rate in some countries is 7 and 8% for males and females, respectively. This pathology generally does not show encouraging results in relation to chemotherapy or radiotherapy. Although without full consensus, it is believed that males are more likely to be affected. Discussion and Conclusions: Part of pancreatic cancers may have an occupational origin through contact with ionizing radiation and, above all, some chemical agents: pesticides, fertilizers, cadmium, nickel (and other heavy metals), nitrosamines, chlorinated and polycyclic aromatics hydrocarbons, silica/asbestos, metallurgy fluids, paints and diesel fumes. Thus, the most relevant professional sectors will be agriculture and gardening, dry cleaning, construction/shipbuilding (and related areas), as well as photography. Taking into account the scarcity of data at a national level, it would be relevant to obtain studies that explore this phenomenon, namely, which levels of exposure to risk factors potentially carcinogenic, which professions are most exposed, which protection measures have been equated, as well as its effectiveness or even the rate of return to work and its eventual limitations.
Introduction/framework/objectives: Pancreatic cancer has a high mortality rate. Part of the etiology, for some researchers, may be related to work activities, so knowledge of risk factors may be important for the performance of Occupational Health and Security teams. Thus, taking into account that the evidence on the subject is scarce, the aim of this review was to summarize the available and most current information. Methodology: This is a Bibliographic Review, initiated through a search carried out in January 2022 in the databases āCINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: comprehensive, MedicLatina and RCAAPā. Content: In 2008, around 280,000 new cases were estimated worldwide. Due to the low survival rate, the incidence number is similar to the mortality rate in the medium term. The five-year survival rate in some countries is 7 and 8% for males and females, respectively. This pathology generally does not show encouraging results in relation to chemotherapy or radiotherapy. Although without full consensus, it is believed that males are more likely to be affected. Discussion and Conclusions: Part of pancreatic cancers may have an occupational origin through contact with ionizing radiation and, above all, some chemical agents: pesticides, fertilizers, cadmium, nickel (and other heavy metals), nitrosamines, chlorinated and polycyclic aromatics hydrocarbons, silica/asbestos, metallurgy fluids, paints and diesel fumes. Thus, the most relevant professional sectors will be agriculture and gardening, dry cleaning, construction/shipbuilding (and related areas), as well as photography. Taking into account the scarcity of data at a national level, it would be relevant to obtain studies that explore this phenomenon, namely, which levels of exposure to risk factors potentially carcinogenic, which professions are most exposed, which protection measures have been equated, as well as its effectiveness or even the rate of return to work and its eventual limitations.
Descrição
Palavras-chave
Cancro do pâncreas Cancro pancreÔtico Medicina do trabalho Occupational health Occupational medicine Occupational safety Pancreatic cancer Pesticidas Pesticides Saúde ocupacional Segurança no trabalho
Contexto Educativo
Citação
Santos, M., Almeida, A., & Lopes, C. (2023). Cancro pancreÔtico associado ao trabalho. Revista Portuguesa de Saúde Ocupacional Online, (15), Article esub402. https://doi.org/10.31252/RPSO/17.06.2023
Editora
LicenƧa CC
Sem licenƧa CC
