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Histological and immunohistochemical analysis of a nanobiomaterial in a maxillary sinus lift surgery: a case report

dc.contributor.authorLopes, João Carlos Amorim
dc.contributor.authorSalviano, Saulo Henrique
dc.contributor.authorLins, Consuelo Antunes Barreto
dc.contributor.authorDevita, Renan Lana
dc.contributor.authorBrum, Igor da Silva
dc.contributor.authorFernandes, Gustavo Vicentis de Oliveira
dc.date.accessioned2022-12-21T10:40:21Z
dc.date.available2022-12-21T10:40:21Z
dc.date.issued2020
dc.description.abstractThe objective of this study was to histologically and immunologically analyze the level of bone substitution and the presence of new blood vessels in a nanobiomaterial composed of hydroxyapatite and BTCP in a maxillary sinus lift surgery. A case of a maxillary sinus lift was investigated. The patient had a 1.0 mm bone remnant on the left side and 2 grams of nanobiomaterial (80% hydroxyapatite and 20% β-tricalcium phosphate) were grafted into the pneumatized sinus. After 6 months, during dental implant placement surgery, grafted bone samples were collected with 4 mm trephines. These samples were sent to the laboratory for analysis where they were stained with masson'strichrome and immuno stained with osteonectin and osteopontin. After 6 months of bone regeneration a result of 14 mm of bone gain was reached, the analyzes in masson's trichrome showed an excellent gain of newly formed bone, in addition to a very high percentage of blood vessels. In the immunostaining, a very large number of osteoblasts and osteoclasts was observed, signaling an excellent osteoconduction and osteoinduction of the studied nanobiomaterial. The maxillary sinus lift surgery with nanobiomaterial provided a very favorable bone height and thickness gain, as well as the high vascularity and cellularity, which enabled the patient's oral rehabilitation with osseointegrated dental implants and permanent ceramic prostheses.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.issn2394-2967
dc.identifier.urihttp://hdl.handle.net/10400.14/39609
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectBone grafpt_PT
dc.subjectDental implantspt_PT
dc.subjectMaxillary sinus lift surgerypt_PT
dc.subjectHydroxyapatitept_PT
dc.titleHistological and immunohistochemical analysis of a nanobiomaterial in a maxillary sinus lift surgery: a case reportpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage27pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPage13pt_PT
oaire.citation.titleBritish Journal of Medical and Health Researchpt_PT
oaire.citation.volume7pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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