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Sialochemical analysis in polytraumatized patients in intensive care units

2019-10-01Artigo científico Acesso aberto
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dc.contributor.authorChaves, Maria Heloisa Madruga
dc.contributor.authorWolf, Amanda Rebeca da Silveira
dc.contributor.authorNascimento, Kelly Aline Lima
dc.contributor.authorNawcki, Danielle
dc.contributor.authorFeustel, Gabriele Muller
dc.contributor.authorBettega, Patricia Vida Cassi
dc.contributor.authorIgnacio, Sergio Aparecido
dc.contributor.authorBrancher, João Armando
dc.contributor.authorTannous, Luana Alves
dc.contributor.authorWerneck, Renata Iani
dc.contributor.authorSouza, Paulo Henrique Couto
dc.contributor.authorBarros, Marlene Maria Tourais de
dc.contributor.authorJohann, Aline Cristina Batista Rodrigues
dc.date.accessioned2021-04-13T15:39:50Z
dc.date.available2021-04-13T15:39:50Z
dc.date.issued2019-10-01
dc.description.abstractThe profiles of polytraumatized patients in intensive care units were characterized. Serum and salivary markers were compared with normality between Classes I and II of APACHE II and between periods of hospitalization; these results were correlated. This was a prospective study on saliva charts and collection (n = 70). Profile: male, 27 years old, blunt traumas and collisions. Serum parameters with normality: decrease in pH, creatinine at admission to Class I, and at 48 and 72 hours in both classes; K+ at 48 h in Class II; Ca+ on admission in both classes and at 72 h in Class I. Increase in urea at 72 h in Class II, glucose at all times and in all classes, and Ca+ at 48 h in both classes. Class II had high Na+ at 48 and 72 h compared to Class I. In Class I, creatinine reduction occurred in 48 h and 72 h compared to admission and an increase of Ca+ at 48 h with admission. In Class II, pH and Na+ increased at 48 h and 72 h compared to admission. K+ decreased from admission to 48 h and increased from 48 h to 72 h. Urea increased from 48 to 72 hours. Creatinine decreased from admission to 48 and 72 hours. Ca+ increased from admission to 48 hours and decreased from 48 to 72 hours. There was an increase in the saliva levels in both classes and times in relation to normality. There was an increase in urea at admission, glucose at 72 h, and Ca+ at 48 h in Class II compared with Class I. Class I urea increased from admission to 48 h and Ca+ decreased from admission to 48 h. Class II urea decreased from 48 h to 72 h. Strong or very strong positive correlation was identified between blood and creatinine saliva at all times and regular and negative Ca+ at 72 h. This study provides evidence that salivary and serum biomarkers can be used together to monitor the evolution of the clinical symptoms of ICU patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1371/journal.pone.0222974pt_PT
dc.identifier.eid85072837866
dc.identifier.issn1932-6203
dc.identifier.pmcPMC6776458
dc.identifier.pmid31581248
dc.identifier.urihttp://hdl.handle.net/10400.14/32543
dc.identifier.wos000532398600024
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleSialochemical analysis in polytraumatized patients in intensive care unitspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue10pt_PT
oaire.citation.titlePLoS ONEpt_PT
oaire.citation.volume14pt_PT
person.familyNameBrancher
person.familyNameWerneck
person.familyNameCouto Souza
person.familyNameBarros
person.givenNameJoão Armando
person.givenNameRenata
person.givenNamePaulo Henrique
person.givenNameMarlene
person.identifierAAG-6405-2021
person.identifier.ciencia-id3211-1B4F-C7F6
person.identifier.orcid0000-0002-8914-702X
person.identifier.orcid0000-0003-1134-5357
person.identifier.orcid0000-0003-3655-397X
person.identifier.orcid0000-0003-0631-4062
person.identifier.ridC-7758-2014
person.identifier.ridG-3014-2012
person.identifier.ridI-9989-2016
person.identifier.scopus-author-id24402609700
person.identifier.scopus-author-id19036622100
person.identifier.scopus-author-id8325686200
person.identifier.scopus-author-id7102895790
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication88654824-8114-4b18-8abb-1140f8c9f29b
relation.isAuthorOfPublication30aee4e0-0264-497e-bea1-b57a16532abf
relation.isAuthorOfPublication9d5db66d-8efa-48fb-a067-57c6e3178b77
relation.isAuthorOfPublication70f0c477-8ded-40f6-b068-44695d474a20
relation.isAuthorOfPublication.latestForDiscovery9d5db66d-8efa-48fb-a067-57c6e3178b77

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