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This meeting report summarises the proceedings of a panel-led symposium that took place at the European Wound Management Association (EWMA) Conference,Amsterdam in May 2017. It looks at the crucial role of pressure injury prevention and the importance of robust clinical data in proving the positive impact — for patients, clinicians and the healthcare economy — of implementing strategies that include the use of prophylactic dressings, positioners, and turning and positioning systems. The expert panel provided guidance on how to implement changes in line with evidence-based consensus, and highlighted the importance of delivering optimal care to at-risk patients.