Centro de Investigação Interdisciplinar em Saúde (CIIS)
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Browsing Centro de Investigação Interdisciplinar em Saúde (CIIS) by Sustainable Development Goals (SDG) "03:Saúde de Qualidade"
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- 17 de novembro - dia internacional da prematuridadePublication . Romeiro, Joana; Cristina Martins, Ana
- A 3D cell culture model of the Tuberculosis granuloma that can be applied for host genetic studies in the context of a multicellular immunologic response to infectionPublication . David, Susana; Mandal, Manoj; Anes, Elsa; Pires, David
- Ansiedade, depressão e ideação suicida em idade pediátrica: uma visão sobre as repercussões da pandemia COVID-19Publication . Carneiro, Liliana; Pires, Telma; Romeiro, Joana; Ramos, Sílvia; Charepe, Zaida
- "Call for terms of axes": towards completeness of the nursing diagnoses' labelsPublication . Miguel, Susana; Romeiro, Joana; Casaleiro, Tiago; Martins, Helga; Caldeira, Sílvia
- Changing life expectancy in European countries 1990-2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021Publication . GBD 2021 Europe Life Expectancy Collaborators; Steel, Nicholas; Bauer-Staeb, Clarissa Maria Mercedes; Ford, John A.; Abbafati, Cristiana; Abdalla, Mohammed Altigani; Abdelkader, Atef; Abdi, Parsa; Zuñiga, Roberto Ariel Abeldaño; Abiodun, Olugbenga Olusola; Abolhassani, Hassan; Abu-Gharbieh, Eman; Abukhadijah, Hana J.; Abu-Zaid, Ahmed; Addo, Isaac Yeboah; Addolorato, Giovanni; Adekanmbi, Victor; Adetunji, Juliana Bunmi; Adeyeoluwa, Temitayo Esther; Agardh, Emilie E.; Agyemang-Duah, Williams; Ahmad, Danish; Ahmed, Anisuddin; Ahmed, Ayman; Ahmed, Syed Anees; Akinosoglou, Karolina; Akkaif, Mohammed Ahmed; Al Awaidy, Salah; Al Hasan, Syed Mahfuz; Al Zaabi, Omar Ali Mohammed; Aldridge, Robert W.; Algammal, Abdelazeem M.; Al-Gheethi, Adel Ali Saeed; Ali, Abid; Ali, Mohammed Usman; Ali, Syed Shujait; Ali, Waad; Alicandro, Gianfranco; Alif, Sheikh Mohammad; Al-Jumaily, Adel; Allebeck, Peter; Alrawashdeh, Ahmad; Al-Rifai, Rami H.; Alsabri, Mohammed A.; Alshahrani, Najim Z.; Aluh, Deborah Oyine; Al-Wardat, Mohammad; Al-Zyoud, Walid A.; Amiri, Sohrab; Anderlini, Deanna; Bettencourt, Paulo J.G.Background: Decades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and cause-specific death rates in different European countries related to changes in life expectancy in those countries before and during the COVID-19 pandemic. Methods: We used data and methods from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to compare changes in life expectancy at birth, causes of death, and population exposure to risk factors in 16 European Economic Area countries (Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, and Sweden) and the four UK nations (England, Northern Ireland, Scotland, and Wales) for three time periods: 1990–2011, 2011–19, and 2019–21. Changes in life expectancy and causes of death were estimated with an established life expectancy cause-specific decomposition method, and compared with summary exposure values of risk factors for the major causes of death influencing life expectancy. Findings: All countries showed mean annual improvements in life expectancy in both 1990–2011 (overall mean 0·23 years [95% uncertainty interval [UI] 0·23 to 0·24]) and 2011–19 (overall mean 0·15 years [0·13 to 0·16]). The rate of improvement was lower in 2011–19 than in 1990–2011 in all countries except for Norway, where the mean annual increase in life expectancy rose from 0·21 years (95% UI 0·20 to 0·22) in 1990–2011 to 0·23 years (0·21 to 0·26) in 2011–19 (difference of 0·03 years). In other countries, the difference in mean annual improvement between these periods ranged from –0·01 years in Iceland (0·19 years [95% UI 0·16 to 0·21] vs 0·18 years [0·09 to 0·26]), to –0·18 years in England (0·25 years [0·24 to 0·25] vs 0·07 years [0·06 to 0·08]). In 2019–21, there was an overall decrease in mean annual life expectancy across all countries (overall mean –0·18 years [95% UI –0·22 to –0·13]), with all countries having an absolute fall in life expectancy except for Ireland, Iceland, Sweden, Norway, and Denmark, which showed marginal improvement in life expectancy, and Belgium, which showed no change in life expectancy. Across countries, the causes of death responsible for the largest improvements in life expectancy from 1990 to 2011 were cardiovascular diseases and neoplasms. Deaths from cardiovascular diseases were the primary driver of reductions in life expectancy improvements during 2011–19, and deaths from respiratory infections and other COVID-19 pandemic-related outcomes were responsible for the decreases in life expectancy during 2019–21. Deaths from cardiovascular diseases and neoplasms in 2019 were attributable to high systolic blood pressure, dietary risks, tobacco smoke, high LDL cholesterol, high BMI, occupational risks, high alcohol use, and other risks including low physical activity. Exposure to these major risk factors differed by country, with trends of increasing exposure to high BMI and decreasing exposure to tobacco smoke observed in all countries during 1990–2021. Interpretation: The countries that best maintained improvements in life expectancy after 2011 (Norway, Iceland, Belgium, Denmark, and Sweden) did so through better maintenance of reductions in mortality from cardiovascular diseases and neoplasms, underpinned by decreased exposures to major risks, possibly mitigated by government policies. The continued improvements in life expectancy in five countries during 2019–21 indicate that these countries were better prepared to withstand the COVID-19 pandemic. By contrast, countries with the greatest slowdown in life expectancy improvements after 2011 went on to have some of the largest decreases in life expectancy in 2019–21. These findings suggest that government policies that improve population health also build resilience to future shocks. Such policies include reducing population exposure to major upstream risks for cardiovascular diseases and neoplasms, such as harmful diets and low physical activity, tackling the commercial determinants of poor health, and ensuring access to affordable health services. Funding: Gates Foundation.
- Cirurgia de cancro de cabeça e pescoço: a especificidade dos cuidados à pessoa com faringostoma e esofagostomaPublication . Pires, Lucinda; Frade, Inês; Almeida, Anabela; Miguel, SusanaTemos como objetivo descrever os cuidados específicos à pessoa com faringostoma e esofagostoma, impulsionadores da melhoria da prática clínica e da qualidade de vida da pessoa. Cirurgias como a laringectomia total induzem enorme impacto físico, social e emocional na pessoa e família, cujas consequências e possíveis complicações são potenciadas quando seguidas da confeção de um faringostoma e esofagostoma. A pessoa com faringostoma e esofagostoma requer cuidados diferenciados que incluem a realização do penso, vigilância e cuidados específicos, não esquecendo os cuida-dos inerentes à ostomia respiratória, bem como a todas as outras dimensões da pessoa (psicológica, social, cultural e espiritual). Perante toda a complexidade cirúrgica, as pessoas portadoras deste tipo específico de estomas carecem de intervenções de enfermagem especializadas, as quais são baseadas na evidência. E incidem em prevenir complicações e contribuir para a qualidade de vida da pessoa, justificando-se igualmente a necessidade de intervenção de toda a equipa multidisciplinar.
- Clinical validation of nursing diagnoses in vulnerable patients: the adequacy of different methodsPublication . Miguel, Susana; Romeiro, Joana; Casaleiro, Tiago; Martins, Helga; Caldeira, Sílvia
- Cognitive impairment in prostate cancer patients receiving androgen deprivation therapy: a scoping reviewPublication . Barreira, João Vasco; Barreira, Pedro; Falcão, Gil; Garcez, Daniela; Silva, Pedro; Santos, Gustavo; Fontes-Sousa, Mário; Mendes, José Leão; Reis, Filipa; Santos, Carla F.; Ribeiro, Filipa; Capelas, Manuel LuísBackground: Androgen deprivation therapy (ADT) is a primary treatment for prostate cancer (PCa) that effectively reduces androgen levels to suppress tumor progression. However, growing evidence suggests potential cognitive side effects, raising concerns about the long-term neurological consequences of this treatment. Objective: This scoping review aims to synthesize the existing evidence linking ADT to cognitive changes in men with PCa, identifying the key cognitive domains affected and outlining gaps in the existing literature. Methods: A systematic literature search was conducted according to the PRISMA-ScR guidelines in CINAHL, PubMed, Scopus, and Web of Science. Studies investigating cognitive function in ADT-treated PCa patients were included, covering randomized controlled trials (RCTs) and cohort, case–control, and cross-sectional studies. The extracted data included the study design, evaluated cognitive characteristics, measurement tools, and overall findings. Results: A total of 22 studies met the inclusion and exclusion criteria. Cognitive assessments varied across studies. While some studies reported cognitive impairments in ADT-treated patients—particularly in working, verbal, and visual memory and executive function—others found no significant effects. The variability in prostate cancer staging, epidemiological study designs, and treatment regimens; the exclusion of comorbid conditions; and the differences in assessment tools, sample sizes, and study durations hinder definitive conclusions about the cognitive effects of ADT. Conclusions: This scoping review highlights the heterogeneous and often contradictory evidence regarding ADT-associated cognitive dysfunction. While certain cognitive domains may be affected, methodological inconsistencies limit robust conclusions. Standardized cognitive assessments and longer longitudinal studies are required to clarify ADT’s role in cognitive decline. As the PCa survival rate increases with extended ADT use, integrating routine cognitive monitoring into clinical practice should be considered for PCa patients.
- O conceito de vulnerabilidade social e a sua emergência em processos de saúde-doençaPublication . Romeiro, Joana; Caldeira, Sílvia
- O conselho de saúde pública, uma imanência da revolução de 1820Publication . Subtil, Carlos Louzada LopesO ano do bicentenário da Revolução de 1820 decorre em simultâneo com a ocorrência da maior pandemia que assola a humanidade, depois da peste negra, da varíola, da cólera ou da gripe espanhola e trouxe à cena a Direção-Geral da Saúde (DGS). Com recurso à legislação régia e aos debates parlamentares no período da Monarquia Constitucional, pretende-se revisitar este momento histórico para traçar a genealogia da DGS, nas várias formas que foi assumindo desde a Revolução Vintista à implantação da República, com destaque para a criação do Conselho de Saúde Pública, gizado por Passos Manuel, em 1836. A par de outros problemas da saúde pública, o medo do contágio de doenças infeciosas foi o pretexto e o principal impulsionador de mudanças organizativas na administração da saúde. Durante todo este período, acabou por vingar o biopoder, uma nova forma de poder sobre os corpos decorrente do novo paradigma higienista.