Browsing by Issue Date, starting with "2024-03-15"
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- Relação dos “pilares invisíveis da família de origem” com satisfação e ajustamento diádico nos relacionamentos amorosos em adultosPublication . Silva, Mariana Daniels Moura da; Ramalho, Carla Susana Rodrigues da CostaA perceção que cada indivíduo carrega da experiência familiar prévia se mostra relevante para a escolha, manutenção ou dissolução do relacionamento amoroso na idade adulta. O presente trabalho surgiu com o objetivo de explorar a relação entre a perceção pessoal dos pilares da família de origem e os relacionamentos amorosos, especificamente com a relação entre os fatores de proximidade e projeção na família de origem, o ajustamento diádico e satisfação na relação. Foram investigados dados recolhidos de uma amostra de 212 indivíduos adultos com experiência presente num relacionamento amoroso; explorando ainda a relação de variáveis sociodemográficas, pessoais e familiares, com a perceção dos pilares da família de origem, o ajustamento diádico e satisfação na relação. Os dados evidenciam que há uma associação positiva e estatisticamente significativa de todos os quatro pilares da família de origem - intimidade, continuidade, coesão e transcendência - com a satisfação e com o consenso, bem como que a perceção sobre a família de origem se correlaciona com a satisfação nos relacionamentos amorosos. Ademais, os resultados também evidenciaram uma relação do tipo de compromisso dos pais com a perceção dos pilares na família de origem, dando conta de dinâmicas relevantes na experiência familiar passada e presente.
- Why and when is meaningful work important for performance? : the roles of PsyCap and workloadPublication . Cortinhal, Filipa Duarte do; Marques, Tatiana Pires“It is impossible to have a great life unless it is a meaningful life. And it is very difficult to have a meaningful life without meaningful work.” James C. Collins. The alignment and balanced development of mental health and economics and business are crucial for the well-being of individuals and the global community. The subject of happiness and the perception of meaningful work has garnered significant attention in academic research, particularly in the field of human resources management. However, despite the growing body of literature on this topic, a comprehensive understanding of the impact of meaningful work on job performance remains difficult to determine. In light of the significance and growing attention surrounding these subjects, a research investigation was conducted to explore the correlation between meaningful work and job performance, with Psycap acting as a potential mediating factor and workload acting as a potential moderating factor. The present study involved a sample of 204 Portuguese employees hailing from various companies and sectors. As hypothesised, a significant indirect relationship was observed between meaningful work, PsyCap and job performance. However, contrary to initial estimations, the moderating influence of workload was not observed.
- Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregatesPublication . Marques, Mariana; Ramos, Bruno; Albuquerque, Hélio; Pereira, Marisa; Ribeiro, Diana Roberta; Nunes, Alexandre; Sarabando, Jéssica; Brás, Daniela; Ferreira, Ana Rita; Vitorino, Rui; Amorim, Maria João; Silva, Artur M. S.; Soares, Ana Raquel; Ribeiro, DanielaInfluenza A virus (IAV) employs multiple strategies to manipulate cellular mechanisms and support proper virion formation and propagation. In this study, we performed a detailed analysis of the interplay between IAV and the host cells’ proteostasis throughout the entire infectious cycle. We reveal that IAV infection activates the inositol requiring enzyme 1 (IRE1) branch of the unfolded protein response, and that this activation is important for an efficient infection. We further observed the accumulation of virus-induced insoluble protein aggregates, containing both viral and host proteins, associated with a dysregulation of the host cell RNA metabolism. Our data indicate that this accumulation is important for IAV propagation and favors the final steps of the infection cycle, more specifically the virion assembly. These findings reveal additional mechanisms by which IAV disrupts host proteostasis and uncovers new cellular targets that can be explored for the development of host-directed antiviral strategies.