Browsing by Issue Date, starting with "2022-12-08"
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- MACE — colecção António Cachola quinze anos atos de colecionar, atos [coletivos] de [poder] mudarPublication . Santos, LuísaHá cinco anos, a propósito do 10º aniversário do Museu de Arte Contemporânea de Elvas [MACE], casa da Coleção António Cachola, escrevia aqui, na Revista Contemporânea, que colecionar é um ato de conhecer. Hoje, a partir da celebração dos 15 anos da abertura ao público da coleção António Cachola, em 2007 [6 seis anos depois da assinatura do protocolo que deu início à coleção], proponho que, sendo intrinsecamente um ato de conhecer, colecionar é também um ato simultaneamente de poder coletivo na medida em que, no seu melhor e colaborativamente, pode mudar as realidades sociais tal como as conhecemos.
- Microbial production of terpenesPublication . Pimentel, Lígia; Carsanba, Erdem; Teixeira, Francisca; Vidigal, Susana; Pintado, Manuela; Oliveira, Carla; Rodríguez-Alcalá, Luis M.Sustainability is one of the main challenges facing humankind in the twenty-first century due to the continuous increase in the demand for energy and resources that characterizes our current industrial activity, driven in part by exponential population growth. This problem can be tackled from different strategies and among them the search for biomolecules, either recovered through processes based on the circular economy or through synthetic biology, are highly promising. In this sense, terpenes, the largest family of secondary metabolites in the plant kingdom, have attracted much of the research in recent decades in pursuit of alternative, more ecological, and sustainable ways for their obtention. The reasons for this interest are due to their extensive structural diversity and the possibility of gaining new functionalities, simply by chemical modification, which also makes them excellent candidates in areas such as biomaterials and pharmaceuticals. But also, the fact that the natural biosynthetic pathways of terpenes are well known from the point of view of metabolites and enzymes facilitates their industrial production using genetically modified microorganisms. This chapter aims to give the reader a broad but at the same time comprehensive view of the production of microbial terpenes in a sustainability context. Starting by the circumstances that lead to the need to look for renewable sources of biomolecules and following by why terpenes represent a very promising opportunity even if only their characteristics from a chemical and bioactivity point of view were considered. Finally, it will be discussed which microorganisms can produce these unique lipids and how, the main option followed nowadays is using synthetic biology strategies, involving modified organisms that are already being used on an industrial scale for applications ranging from biofuels to pharmaceuticals.
- Hope aspects of the women’s experience after confirmation of a high-risk pregnancy condition: a systematic scoping reviewPublication . Antunes, Mónica; Viana, Clara Roquette; Charepe, ZaidaBackground: Pregnancy is a period of transformation, hope, expectation, and worry for women and their families. A high-risk pregnancy refers to a pregnancy in which the mother and/or fetus are at greater-than-normal risk of complications, and it evokes a range of emotional and psychological experiences that largely depend on the care and support provided by health professionals. The purpose of this review is to summarize the existing literature on the lived experience of hope in women facing a high-risk pregnancy related to their own health and/or medical conditions related to the fetus. Methods: This review followed the Joanna Briggs Institute’s methodology. No limits on a date were applied to the search. Identified titles and abstracts were screened to select original reports and were cross-checked for any overlap of cases. We included studies that emphasized the experience of hope of pregnant women dealing with a pregnancy complication. Main Results: According to the results of the present scoping review, we found two main dimensions: women experiencing a high-risk pregnancy themselves and prenatal diagnosis. In both cases, the women were in a dilemma between hope and hopelessness. Conclusion: The findings demonstrate that women facing high-risk pregnancies struggle with multiple fears and concerns about their own health and the fetus’s health. Further research is needed to identify best practices for the care provided to the vulnerable populations.