Browsing by Author "Coppola, Gianluca"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- Correction to: The role of community pharmacists in managing common headache disorders, and their integration within structured headache services: position statement on behalf of the European Headache Federation (EHF) and Lifting The Burden (LTB: the Global Campaign against Headache), with the formal endorsement of the International Pharmaceutical Federation (The Journal of Headache and Pain, (2025), 26, 1, (100), 10.1186/s10194-025-02021-3)Publication . Banihani, Heba; Lampl, Christian; Maassenvandenbrink, Antoinette; Amin, Faisal Mohammad; Carlsen, Louise Ninett; Coppola, Gianluca; Deligianni, Christina; Gil-Gouveia, Raquel; Holland, Philip R.; Husoy, Andreas K.; Jensen, Rigmor; Plácido, Madalena; Reuter, Uwe; Ryliskiene, Kristina; Rio, Margarita Sanchez del; Schytz, Henrik Winther; Tronvik, Erling; Versijpt, Jan; Steiner, Timothy J.Correction: J Headache Pain 26, 100 (2025) In this article, the text “on behalf of the European Headache Federation, the Norwegian Centre for Headache Research (NorHead) and Lifting The Burden: the Global Campaign against Headache” has been removed from the author list because it erroneously duplicated text from the article title.
- Hallmarks of primary headache: part 3 - cluster headachePublication . Coppola, Gianluca; Arruda, Marco Antônio; Ashina, Messoud; Barloese, Mads; Belin, Andrea Carmine; Bottiroli, Sara; Chowdhury, Debashish; Icco, Roberto De; Lorenzo, Cherubino di; Stefano, Giulia Di; Edvinsson, Jacob C. A.; Evers, Stefan; Ferraro, Stefania; Fronczek, Rolf; García-Azorín, David; Goadsby, Peter J.; Grazzi, Licia; Holle, Dagny; Jansen, Julia J.; Gil-Gouveia, Raquel; Lambru, Giorgio; Lanteri-Minet, Michel; Lisicki, Marco; Mitsikostas, Dimos D.; Monteith, Teshamae; Montisano, Danilo Antonio; Obermann, Mark; Pan, Li Ling Hope; Peng, Kuan Po; Peres, Mario; Petrušic, Igor; Cecchini, Alberto Proietti; Vila-Pueyo, Marta; Raggi, Alberto; Rainero, Innocenzo; Sandrini, Giorgio; Sebastianelli, Gabriele; Takizawa, Tsubasa; Tanprawate, Surat; Tassorelli, Cristina; Truini, Andrea; Valeriani, Massimiliano; Vuralli, Doga; Waliszewska-Prosół, Marta; Wang, Shuu Jiun; Wang, Yonggang; Wijeratne, Tissa; Martelletti, PaoloBackground: Cluster headache (CH) is a rare primary headache disorder characterized by recurrent episodes of strictly unilateral excruciating pain accompanied by trigemino-autonomic signs, which significantly impacts the quality of life, social interactions, and occupational functioning of those who are affected. To promote a better understanding of this disabling condition and to foster research on the topic, this review provides a comprehensive description of the hallmarks of CH, including its clinical presentation, diagnostic challenges, pathophysiology, and current and novel therapeutic targets. It concludes by describing the disease burden and advocating for significant improvements in healthcare systems, and promoting health equity, as well as reducing stigma. Principal findings: Despite its distinctive clinical and chronobiological features, CH may be mistaken for other primary headache disorders or different types of orofacial pain. Key pathogenic characteristics include the activation of the trigeminal-autonomic system with the release of several neuropeptides, the involvement of the hypothalamus in regulating the circadian rhythm, genetic variants, and the mesolimbic system. Both invasive and non-invasive neuromodulation treatments have been used to target the trigemino-cervical, parasympathetic, and hypothalamic systems. Additionally, novel therapeutic targets are currently being study. Alongside canonical therapies, several complementary approaches have been explored over the years, with most evidence deriving from uncontrolled research involving individuals who do not respond to standard pharmacological treatments. Despite advancements in our understanding of this complex disease, CH continues to pose considerable social, economic, and psychological challenges. Advocacy is essential and should prioritize early diagnosis, alleviate stigma, provide specialized training for healthcare professionals, and offer support to and through patient associations. Conclusions: CH is characterised by a complex, multifactorial, pathophysiology that is still not fully understood. Precise diagnosis, additional research studies, and robust psychosocial and institutional support are necessary to improve the quality of life for individuals affected by this debilitating condition.
- The role of community pharmacists in managing common headache disorders, and their integration within structured headache services: position statement on behalf of the European Headache Federation (EHF) and Lifting The Burden (LTB: the Global Campaign against Headache), with the formal endorsement of the International Pharmaceutical FederationPublication . BaniHani, Heba; Lampl, Christian; MaassenvandenBrink, Antoinette; Amin, Faisal Mohammad; Carlsen, Louise Ninett; Coppola, Gianluca; Deligianni, Christina; Gil-Gouveia, Raquel; Holland, Philip R.; Husøy, Andreas K.; Jensen, Rigmor; Plácido, Madalena; Reuter, Uwe; Ryliškienė, Kristina; Río, Margarita Sanchez del; Schytz, Henrik Winther; Tronvik, Erling; Versijpt, Jan; Steiner, Timothy J.In the sustainable development goals (SDG) context of seeking universal health coverage, the expanding gap between the supply of specialized and primary health-care providers of headache-related health care and the care needs of the very large number of people affected by headache is a formidable but not insoluble public-health challenge. Structured headache services provide a cost-effective framework wherein controlled patient flows enable the care needs of people with headache to be met at appropriate levels, but these services may still be overwhelmed by inappropriate demand. Community pharmacists are an underutilized resource, potentially well able to provide the solution. To do so, they must, as a profession, be integrated into structured headache services. What remains to be determined is how to achieve this integration in an encouraging climate for change, which recognises the potential for relieving strained health-care systems and meeting a range of health-care needs by expanding pharmacists’ scope of practice. This position statement on behalf of the European Headache Federation (EHF) and Lifting The Burden (LTB) is formally endorsed by the International Pharmaceutical Federation (FIP).