Repository logo
 
Publication

In vitro fermentation of lupin seeds (Lupinus albus) and broad beans (Vicia faba): dynamic modulation of the intestinal microbiota and metabolomic output

2015Journal article Restricted access
Simple item page
dc.contributor.authorGullón, Patricia
dc.contributor.authorTavaria, Freni
dc.contributor.authorVasconcelos, Marta
dc.contributor.authorGomes, Ana Maria
dc.date.accessioned2016-04-21T13:18:17Z
dc.date.available2016-04-21T13:18:17Z
dc.date.issued2015
dc.description.abstractBroad beans (Vicia faba) and lupin seeds (Lupinus albus) are legumes rich in a wide range of compounds, which may represent a useful dietary approach for modulating the human gut microbiome. In this work, after in vitro digestion, legume samples were used as carbon sources in anaerobic batch cultures to evaluate their impact on the intestinal microbiota composition and on their metabolic products. The fermentations were monitored by a decrease in pH, generation of short chain fatty acids (SCFA) and lactate and the changes in the dynamic bacterial populations by fluorescence in situ hybridization (FISH). The total SCFA at the end of fermentation was 81.52 mM for lupin seeds and 78.41 mM for broad beans accompanied by a decrease of the pH for both legumes. The microbial groups that increased significantly (P < 0.05) were Bifidobacterium spp., Lactobacillus-Enterococcus, Atopobium, Bacteroides-Pretovella, Clostridium coccoides-Eubacterium rectale, Faecalibacterium prausnitzii and Roseburia intestinalis. This impact on the intestinal microbiota suggests that lupin seeds and broad beans may be used in the development of novel functional foods, which can be included in dietary strategies for human health promotion.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationGULLÓN, P.; TAVARIA, Freni; VASCONCELOS, Marta; GOMES, Ana M.P. - In vitro fermentation of lupin seeds (Lupinus albus) and broad beans (Vicia faba): dynamic modulation of the intestinal microbiota and metabolomic output. Food & Function. ISSN 2042-6496. Vol. 6 (10), p.3316-3322. DOI: 10.1039/c5fo00675apt_PT
dc.identifier.doi10.1039/c5fo00675apt_PT
dc.identifier.eid84943744095
dc.identifier.eissn2042-650X
dc.identifier.issn2042-6496
dc.identifier.pmid26252418
dc.identifier.urihttp://hdl.handle.net/10400.14/19890
dc.identifier.wos000362656400014
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistry
dc.relationStrategic Project - LA 16 - 2011-2012
dc.titleIn vitro fermentation of lupin seeds (Lupinus albus) and broad beans (Vicia faba): dynamic modulation of the intestinal microbiota and metabolomic outputpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F79942%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/EXPL%2FBBB-BIO%2F1113%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F79941%2F2011/PT
oaire.citation.endPage3322
oaire.citation.issue10
oaire.citation.startPage3316
oaire.citation.titleFood and Function
oaire.citation.volume6
oaire.fundingStreamSFRH
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream3599-PPCDT
oaire.fundingStreamSFRH
person.familyNameGullón Estévez
person.familyNameKekhasharú Tavaria
person.familyNameVasconcelos
person.familyNameGomes
person.givenNamePatricia
person.givenNameFreni
person.givenNameMarta
person.givenNameAna Maria
person.identifier74696
person.identifier162628
person.identifier.ciencia-id1B15-5DAD-7B27
person.identifier.ciencia-idAA12-BFC1-B2E3
person.identifier.orcid0000-0002-2379-7249
person.identifier.orcid0000-0002-6273-6668
person.identifier.orcid0000-0002-5110-7006
person.identifier.orcid0000-0001-7883-2446
person.identifier.ridI-8166-2013
person.identifier.ridB-9944-2013
person.identifier.scopus-author-id24780290200
person.identifier.scopus-author-id6602645613
person.identifier.scopus-author-id14627797100
person.identifier.scopus-author-id57190668768
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication3ad28e83-e719-4658-8b39-284b992a468c
relation.isAuthorOfPublicatione42f563a-5b1e-4586-b302-efabe7ce07da
relation.isAuthorOfPublicationdf60ebb4-3b71-4733-a9e3-bfa4687f5576
relation.isAuthorOfPublicationc18c2fb1-f3dc-4274-a646-23d456432798
relation.isAuthorOfPublication.latestForDiscoverye42f563a-5b1e-4586-b302-efabe7ce07da
relation.isProjectOfPublication74ba3e7a-02fa-4d34-a197-94e46bdd0871
relation.isProjectOfPublication649dc879-e68a-45df-bcc4-1e66a0521a49
relation.isProjectOfPublication99bfbf01-8673-433b-81ae-89d487807161
relation.isProjectOfPublicationc0475685-8dd0-490d-a58b-92b61aba9671
relation.isProjectOfPublication.latestForDiscovery99bfbf01-8673-433b-81ae-89d487807161

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
19319852.pdf
Size:
200.72 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.44 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CBQF - Contribuições em Revistas Científicas / Contribution to Journals