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Evolving trends in next-generation probiotics: a 5W1H perspective

dc.contributor.authorAlmeida, Diana
dc.contributor.authorMachado, Daniela
dc.contributor.authorAndrade, José Carlos
dc.contributor.authorMendo, Sónia
dc.contributor.authorGomes, Ana Maria
dc.contributor.authorFreitas, Ana Cristina
dc.date.accessioned2019-05-21T14:41:20Z
dc.date.available2019-05-21T14:41:20Z
dc.date.issued2020
dc.description.abstractIn recent years, scientific community has been gathering increasingly more insight on the dynamics that are at play in metabolic and inflammatory disorders. These rapidly growing conditions are reaching epidemic proportions, bringing clinicians and researcher’s new challenges. The specific roles and modulating properties that beneficial/probiotic bacteria hold in the context of the gut ecosystem seem to be key to avert these inflammatory and diet-related disorders. Faecalibacterium prausnitzii, Akkermansia muciniphila and Eubacterium hallii have been identified as candidates for next generation probiotics (NGPs) with exciting potential for the prevention and treatment of such of dysbiosis-associated diseases. The challenges of these non-conventional native gut bacteria lie mainly on their extreme sensitivity to O2 traces. If these strains are to be used successfully in food, supplements or drugs they need to be stable and active in humans. In the present review, we present an overall perspective of the most updated scientific literature on the newly called NGPs through the 5W1H (What, Why, Who, Where, When, and How) method, an innovative and attractive problem-solving approach that provides the reader an effective understanding of the issue at hand.pt_PT
dc.description.versionN/Apt_PT
dc.identifier.citationAlmeida, D., Machado, D., Andrade, J. C., Mendo, S., Gomes, A. M., & Freitas, A. C. (2019). Evolving trends in next-generation probiotics: a 5W1H perspective. Critical Reviews in Food Science and Nutrition, 1–14. https://doi.org/10.1080/10408398.2019.1599812pt_PT
dc.identifier.doi10.1080/10408398.2019.1599812pt_PT
dc.identifier.eid85076692391
dc.identifier.eissn1549-7852
dc.identifier.issn1040-8398
dc.identifier.pmid31062600
dc.identifier.urihttp://hdl.handle.net/10400.14/27671
dc.identifier.wos000539355700001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.subjectProbioticspt_PT
dc.subjectAkkermansia muciniphilapt_PT
dc.subjectFaecalibacterium prausnitziipt_PT
dc.subjectEubacterium halliipt_PT
dc.subjectGut microbiotapt_PT
dc.subjectMetabolic and inflammatory disorderspt_PT
dc.titleEvolving trends in next-generation probiotics: a 5W1H perspectivept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1796
oaire.citation.issue11
oaire.citation.startPage1783
oaire.citation.titleCritical Reviews in Food Science and Nutritionpt_PT
oaire.citation.volume60
person.familyNameAlmeida
person.familyNameMachado
person.familyNameAndrade
person.familyNameMendo
person.familyNameGomes
person.familyNameCardoso Freitas Lopes de Freitas
person.givenNameDiana
person.givenNameDaniela
person.givenNameJosé
person.givenNameSonia
person.givenNameAna Maria
person.givenNameAna Cristina
person.identifier684026
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person.identifier.orcid0000-0001-7883-2446
person.identifier.orcid0000-0002-1430-9370
person.identifier.ridE-1095-2011
person.identifier.ridB-9944-2013
person.identifier.scopus-author-id55415967800
person.identifier.scopus-author-id6505928827
person.identifier.scopus-author-id57190668768
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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