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Simulated digestion of olive pomace water-soluble ingredient : relationship between the compounds bioaccessibility and their potential health benefits

2020Journal article Open access
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dc.contributor.authorRibeiro, Tânia
dc.contributor.authorOliveira, Ana
dc.contributor.authorCampos, Débora
dc.contributor.authorNunes, João
dc.contributor.authorVicente, António A.
dc.contributor.authorPintado, Manuela
dc.date.accessioned2020-03-17T12:54:46Z
dc.date.available2020-03-17T12:54:46Z
dc.date.issued2020
dc.description.abstractOlive pomace is a semisolid by-product with a great potential as a source of bioactive compounds. Using its soluble fraction, a liquid-enriched powder (LOPP) was obtained, exhibiting a rich composition in sugars, polyphenols and minerals, with potential antioxidant, antihypertensive and antidiabetic health benefits. To validate LOPP potential as a functional ingredient the effect of the gastrointestinal tract on its bioactive composition and bioactivities was examined. Polyphenols and minerals were the most affected compounds, however, a significant bioaccessibility of potassium and hydroxytyrosol was verified (> 57 %). As a consequence, the LOPP bioactivities were only moderately affected (losses around 50%). For example, 57.82 ± 1.27 % of the recovered antioxidant activity by ORAC was serum - available. From an initial a-glucosidase inhibition activity of 87.11 ± 1.04 %, at least 50% of the initial potential was kept (43.82 ± 1.14 %). Regarding initial ACE inhibitory activity (91.98 ± 3.24 %), after gastrointestinal tract losses, significant antihypertensive activity was retained in the serum-available fraction (43.4 ± 3.65 %). The colon-available fraction also exhibited an abundant composition in phenolics and minerals. LOPP showed to be a potential functional ingredient not only with potential benefits in preventing cardiovascular diseases but also in gut health.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationRibeiro, T.B., Oliveira, A., Campos, D., Nunes, J., Vicente, A.A., Pintado, M. (2020). Simulated digestion of olive pomace water-soluble ingredient: Relationship between the compounds bioaccessibility and their potential health benefits. Food & Functionpt_PT
dc.identifier.doi10.1039/C9FO03000Jpt_PT
dc.identifier.eid85082542375
dc.identifier.issn2042-650X
dc.identifier.pmid32101211
dc.identifier.urihttp://hdl.handle.net/10400.14/29988
dc.identifier.wos000526928500026
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherRoyal Society of Chemistrypt_PT
dc.subjectBioeconomypt_PT
dc.subjectIn vitro digestionpt_PT
dc.subjectMineralspt_PT
dc.subjectPolyphenolspt_PT
dc.subjectAntioxidantpt_PT
dc.subjectAntihypertensivept_PT
dc.subject28 Antidiabeticpt_PT
dc.subjectBioaccessibility indexpt_PT
dc.titleSimulated digestion of olive pomace water-soluble ingredient : relationship between the compounds bioaccessibility and their potential health benefitspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleFood and Functionpt_PT
person.familyNameRibeiro
person.familyNameOliveira
person.familyNameCampos
person.familyNamePintado
person.givenNameTânia
person.givenNameAna
person.givenNameDébora
person.givenNameMaria Manuela
person.identifier1415634
person.identifierD-8675-2016
person.identifier456608
person.identifier.ciencia-id951D-426B-32ED
person.identifier.ciencia-id4713-31C8-A356
person.identifier.ciencia-id1A16-FC5B-3468
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0001-5859-6888
person.identifier.orcid0000-0001-8012-4203
person.identifier.orcid0000-0003-0174-6640
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridJ-3404-2013
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id55937245800
person.identifier.scopus-author-id55250923400
person.identifier.scopus-author-id7004483898
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication9f339c00-a9e2-4633-a088-199909337c2c
relation.isAuthorOfPublicationbc42fa97-aa34-428f-b73f-d4327706efec
relation.isAuthorOfPublication9676a744-8335-428f-a861-3458cd7283f6
relation.isAuthorOfPublicationba387c7d-27c9-4016-895c-b35597e91ebc
relation.isAuthorOfPublication.latestForDiscoverybc42fa97-aa34-428f-b73f-d4327706efec

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