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Evidence-based exercise recommendations to improve functional mobility in older adults - a study protocol for living systematic review and meta-analysis

dc.contributor.authorWollesen, Bettina
dc.contributor.authorYellon, Tamar
dc.contributor.authorLangeard, Antoine
dc.contributor.authorBelkin, Vera
dc.contributor.authorWunderlich, Anna
dc.contributor.authorGiannouli, Eleftheria
dc.contributor.authorQian, Guoping
dc.contributor.authorBernades, Rafael A.
dc.contributor.authorOssowski, Zbigniew
dc.contributor.authorMarusic, Uros
dc.contributor.authorSighdel, Rajesh
dc.contributor.authorNetz, Yael
dc.contributor.authorVolecker-Rehage, Claudia
dc.date.accessioned2025-02-25T15:36:06Z
dc.date.available2025-02-25T15:36:06Z
dc.date.issued2025
dc.description.abstractBackground and objectives: This is a protocol for a living systematic review and meta-analysis. This review will assess the effects of state-of-the-art exercise interventions designed to promote functional mobility. Therefore, after identifying all potential interventions, we will use the F.I.T.T. principles (frequency, intensity, time, type) as well as the physical and health status of the participants as moderators to analyse the mechanisms for the positive benefits of exercise interventions. The main research questions are: Which exercise types are most beneficial for improving functional mobility in various populations of older adults? Which physical exercise characteristics in terms of frequency, intensity, time and duration will achieve the greatest benefit in terms of the defined outcomes, i.e, the functional mobility of older adults? Methods: The systematic literature research according to PRISMA guidelines will search databases like MEDLINE, APA Psych-Info and Web of Science. Inclusion criteria are: healthy older people ≥ 50 years, randomized-controlled trials including exercise intervention and a walking or mobility assessments (eg., TUG, SPPB) as an outcome measure. A preliminary search revealed more than 33,000 hits that will be screened by pairs of independent reviewers. The results will be summarized according to the effects regarding functional mobility and potential dose-response relations via respective meta-analysis. Conclusion: The systematic review will comprise the knowledge of the existing literature with regards to the effects of the physical activity interventions compared to an active or inactive control group. We will summarize the effects with respect to the F.I.T.T. They provide a foundation for structuring an optimal exercise training program. If possible, we will also compare interventions from the different categories (eg. cardiovascular, resistance, motor-coordinative, multicomponent or mind-body exercise) as a network analysis and report the influence of moderator variables. Based on the results evidence-based guidelines following GRADE for physical exercise interventions to improve functional mobility in older adults will be provided.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.12688/openreseurope.17823.2pt_PT
dc.identifier.eid85216720627
dc.identifier.issn2732-5121
dc.identifier.pmcPMC11770255
dc.identifier.pmid39871858
dc.identifier.urihttp://hdl.handle.net/10400.14/48286
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectEvidence-based exercisept_PT
dc.subjectFunctional mobilitypt_PT
dc.subjectOlder adultspt_PT
dc.subjectPhysical training interventionspt_PT
dc.titleEvidence-based exercise recommendations to improve functional mobility in older adults - a study protocol for living systematic review and meta-analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleOpen Research Europept_PT
oaire.citation.volume4pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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