Repository logo
 
Publication

PET/CT in patients with breast cancer treated with immunotherapy

2023-05Journal article Open access
Simple item page
dc.contributor.authorVaz, Sofia C.
dc.contributor.authorGraff, Stephanie L.
dc.contributor.authorFerreira, Arlindo R.
dc.contributor.authorDebiasi, Márcio
dc.contributor.authorde Geus-Oei, Lioe Fee
dc.date.accessioned2023-05-31T09:25:19Z
dc.date.available2023-05-31T09:25:19Z
dc.date.issued2023-05
dc.description.abstractSignificant advances in breast cancer (BC) treatment have been made in the last decade, including the use of immunotherapy and, in particular, immune checkpoint inhibitors that have been shown to improve the survival of patients with triple negative BC. This narrative review summarizes the studies supporting the use of immunotherapy in BC. Furthermore, the usefulness of 2-deoxy-2-[18F]fluoro-D-glucose (2-[18F]FDG) positron emission/computerized tomography (PET/CT) to image the tumor heterogeneity and to assess treatment response is explored, including the different criteria to interpret 2-[18F]FDG PET/CT imaging. The concept of immuno-PET is also described, by explaining the advantages of mapping treatment targets with a non-invasive and whole-body tool. Several radiopharmaceuticals in the preclinical phase are referred too, and, considering their promising results, translation to human studies is needed to support their use in clinical practice. Overall, this is an evolving field in BC treatment, despite PET imaging developments, the future trends also include expanding immunotherapy to early-stage BC and using other biomarkers.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/cancers15092620pt_PT
dc.identifier.eid85159624221
dc.identifier.issn2072-6694
dc.identifier.pmcPMC10177398
dc.identifier.pmid37174086
dc.identifier.urihttp://hdl.handle.net/10400.14/41260
dc.identifier.wos000987271100001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectBiomarkerspt_PT
dc.subjectBreast cancerpt_PT
dc.subjectFDGpt_PT
dc.subjectImmune checkpoint inhibitorspt_PT
dc.subjectImmuno-PETpt_PT
dc.subjectImmunotherapypt_PT
dc.subjectmAbpt_PT
dc.subjectPET/TCpt_PT
dc.titlePET/CT in patients with breast cancer treated with immunotherapypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue9pt_PT
oaire.citation.titleCancerspt_PT
oaire.citation.volume15pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
70146598.pdf
Size:
1.31 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.44 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

FM - Contribuições em Revistas Científicas / Contribution to Journals