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Production of antimicrobial chitosan nanoparticles against food pathogens

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dc.contributor.authorMadureira, Ana Raquel
dc.contributor.authorPereira, Adriana
dc.contributor.authorCastro, Pedro M.
dc.contributor.authorPintado, Manuela
dc.date.accessioned2016-01-07T16:59:13Z
dc.date.available2016-01-07T16:59:13Z
dc.date.issued2015
dc.description.abstractChitosan nanoparticles (NPs) may be a promissory delivery system of polyphenols. The main objective of this study was to produce chitosan NPs encapsulated with polyphenols with antimicrobial and antioxidant activity against food pathogens. The NPs produced with low and high molecular weight chitosan (LMWC and HMWC) were successfully obtained showing slight variations in the particle size, in the range 300-600 nm, and zeta potential values in the range 20-30 mV, exhibiting a moderate stability. The best encapsulation performance was obtained for NPs produced with LMWC and the polyphenol rosmarinic acid. The antimicrobial studies proved that all free and encapsulated compounds have inhibitory activity upon the tested bacteria (Bacillus cereus, Escherichia coli O157, Listeria innocua, Staphylococcus aureus, Salmonella typhimurium and Yersinia enterocolitica). The images obtained by electronic microscopy showed that it was possible to obtain NPs capable of affecting the cellular structure of bacteria reinforcing their antimicrobial activity.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationMADUREIRA, Ana Raquel; PEREIRA, Adriana; CASTRO, Pedro M.; PINTADO, M. E. - Production of antimicrobial chitosan nanoparticles against food pathogens. Journal of Food Engineering. ISSN 0260-8774. (2015) 167 (Part B), 210-216pt_PT
dc.identifier.doi10.1016/j.jfoodeng.2015.06.010pt_PT
dc.identifier.eid84942295886
dc.identifier.eissn1873-5770
dc.identifier.issn0260-8774
dc.identifier.urihttp://hdl.handle.net/10400.14/18854
dc.identifier.wos000362856400018
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectAntimicrobial activity: chitosanpt_PT
dc.subjectNanoparticlespt_PT
dc.subjectPolyphenolspt_PT
dc.titleProduction of antimicrobial chitosan nanoparticles against food pathogenspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PEst-OE%2FEQB%2FLA0016%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F71391%2F2010/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FAGR-ALI%2F117808%2F2010/PT
oaire.citation.endPage216
oaire.citation.startPage210
oaire.citation.titleJournal of Food Engineering
oaire.citation.volume167
oaire.fundingStream3599-PPCDT
oaire.fundingStreamSFRH
oaire.fundingStream3599-PPCDT
person.familyNameMadureira
person.familyNameMiranda de Castro
person.familyNamePintado
person.givenNameRaquel
person.givenNamePedro João
person.givenNameMaria Manuela
person.identifierM-4659-2013
person.identifier456608
person.identifier.ciencia-id1C14-25F8-CC07
person.identifier.ciencia-id5112-6B99-DC1F
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0001-6596-1927
person.identifier.orcid0000-0001-7164-8005
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridM-4659-2013
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id8384097900
person.identifier.scopus-author-id57201808340
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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