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Pathogenic and non-pathogenic microbes in the wound microbiome-how to flip the switch

dc.contributor.authorLiegenfeld, Sophie Charlotte
dc.contributor.authorStenzel, Svenja
dc.contributor.authorRembe, Julian-Dario
dc.contributor.authorDittmer, Mandy
dc.contributor.authorRamos, Paulo
dc.contributor.authorStuermer, Ewa Klara
dc.date.accessioned2025-04-02T15:42:47Z
dc.date.available2025-04-02T15:42:47Z
dc.date.issued2025-02-06
dc.description.abstractThe wound microbiome refers to the specific community of microbes, including bacteria, fungi, and other microorganisms, that are present in and around a wound. This microbiome plays a crucial role in wound healing, as it includes both healing-promoting and pathogenic microbes. The balance between these microbes significantly influences the healing process; a balanced microbial colonization can support wound healing and prevent infections, while an overgrowth of pathogenic microbes can lead to delayed healing processes and complications. The composition of the wound microbiome can vary depending on the type of wound, cause, genetic predisposition, and (social) environment. In this scope review, the complex interactions in the wound microbiome will be highlighted and the importance of non-pathogenic microbes for wound healing will be discussed. In addition, possible therapeutic approaches to restore a healthy microbiome and prevent infections will be addressed. A deeper understanding of these dynamics could open up new perspectives for the treatment of wounds and the development of strategies to combat wound infections.eng
dc.identifier.doi10.3390/microbiolres16020039
dc.identifier.eid85218637323
dc.identifier.issn2036-7481
dc.identifier.urihttp://hdl.handle.net/10400.14/52894
dc.identifier.wos001431552400001
dc.language.isoeng
dc.peerreviewedyes
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCommensal microorganisms
dc.subjectHard-to-heal wounds
dc.subjectImmune response
dc.subjectProbiotics
dc.subjectSkin microbiome
dc.titlePathogenic and non-pathogenic microbes in the wound microbiome-how to flip the switcheng
dc.typereview article
dspace.entity.typePublication
oaire.citation.issue2
oaire.citation.titleMicrobiology Research
oaire.citation.volume16
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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