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Strategies to assess the impact of sustainable functional food ingredients on gut microbiota

dc.contributor.authorCarvalho, Nelson Mota de
dc.contributor.authorOliveira, Diana Luazi
dc.contributor.authorCosta, Célia Maria
dc.contributor.authorPintado, Maria Estevez
dc.contributor.authorMadureira, Ana Raquel
dc.date.accessioned2023-06-30T17:22:54Z
dc.date.available2023-06-30T17:22:54Z
dc.date.issued2023-05-31
dc.description.abstractNowadays, it is evident that food ingredients have different roles and distinct health benefits to the consumer. Over the past years, the interest in functional foods, especially those targeting gut health, has grown significantly. The use of industrial byproducts as a source of new functional and sustainable ingredients as a response to such demands has raised interest. However, the properties of these ingredients can be affected once incorporated into different food matrices. Therefore, when searching for the least costly and most suitable, beneficial, and sustainable formulations, it is necessary to understand how such ingredients perform when supplemented in different food matrices and how they impact the host's health. As proposed in this manuscript, the ingredients' properties can be first evaluated using in vitro gastrointestinal tract (GIT) simulation models prior to validation through human clinical trials. In vitro models are powerful tools that mimic the physicochemical and physiological conditions of the GIT, enabling prediction of the potentials of functional ingredients per se and when incorporated into a food matrix. Understanding how newly developed ingredients from undervalued agro-industrial sources behave as supplements supports the development of new and more sustainable functional foods while scientifically backing up health-benefits claims.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.3390/foods12112209pt_PT
dc.identifier.eid85163063373
dc.identifier.issn2304-8158
dc.identifier.pmcPMC10253045
dc.identifier.pmid37297454
dc.identifier.urihttp://hdl.handle.net/10400.14/41505
dc.identifier.wos00100642920000
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectCircular economypt_PT
dc.subjectClinical trialpt_PT
dc.subjectFood matricespt_PT
dc.subjectFunctional ingredientspt_PT
dc.subjectGut microbiotapt_PT
dc.subjectIn vitro modelspt_PT
dc.subjectMetabolomicspt_PT
dc.subjectMetagenomicpt_PT
dc.subjectSupplementationpt_PT
dc.titleStrategies to assess the impact of sustainable functional food ingredients on gut microbiotapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue11pt_PT
oaire.citation.titleFoodspt_PT
oaire.citation.volume12pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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