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Treatment of gingival recession type 1 using coronally advanced flap with leucocytes-platelet rich fibrin: a randomized controlled trial

2026-05-07Artigo de investigação Acesso aberto
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dc.contributor.authorSantos, Nuno Bernardo Malta Dos
dc.contributor.authorFernandes, Gustavo Vicentis Oliveira
dc.contributor.authorMarques, Tiago
dc.contributor.authorSousa, Manuel Correia
dc.contributor.authorCorreia, André
dc.contributor.authorVázquez, María Pilar Batalla
dc.contributor.authorBlanco-Carrión, Juan
dc.date.accessioned2026-05-13T16:29:34Z
dc.date.available2026-05-13T16:29:34Z
dc.date.issued2026-05-07
dc.description.abstractObjective: This study aimed to evaluate the clinical outcomes of gingival recession Type 1 (RT1) treatment using a coronally advanced flap (CAF) alone and in combination with L-PRF at 6 months. Materials and methods: A total of 70 RT1 from 19 patients were included. Participants were randomly assigned to the test group (TG, CAF+L-PRF, n=42) and the control group (CG) (CAF alone, n=28). Clinical parameters were assessed at baseline and at 6 months: the primary outcomes were percentage of root coverage (%RC) and complete root coverage (CRC); and the secondary outcomes included mean root coverage (MRC), changes in gingival thickness (GT) and volumetric tissue gain, recession area reduction, analgesic consumption, healing quality (the Inflammatory Proliferative Remodeling [IPR] score), and patient-reported outcome measures (PROMs). Statistical analyses were performed to determine differences between groups; a random-intercept mixed-effects model was used for all site-level outcomes. Results: At six months, %RC was 89.30% ± 20.33% (TG) and 81.60% ± 27.93% (CG) (p>0.05). For the TG and CG, respectively, %CRC was 73.81% and 57.14%; the mean GT gain was 0.16±0.10 mm and 0.11±0.10 mm (p=0.08); the mean volume gain was 1.13±1.25 mm3 and 0.86±0.84 mm3 (p=0.32); the mean number of pills taken was 1.67±0.98 and 2.25±1.02 (p=0.04); the esthetic satisfaction was 95% ± 5% and 90% ± 7% (p=0.31); willingness to undergo the procedure again: 93% ± 4% and 88% ± 6% (p=0.22); sensitivity reduction: 85% ± 6% and 80% ± 8% (p=0.19). There was no statistically significant difference in healing quality and PROMs. Conclusion: Both CAF alone and CAF combined with L-PRF yielded comparable clinical and volumetric outcomes in RT1 treatments. No statistically significant advantages were observed with the adjunctive use of L-PRF. Clinical relevance: Because CAF alone achieves high predictability for RT1 defects, the routine adjunctive use of L-PRF provides limited additional clinical benefits.<p/>eng
dc.identifier.doi10.1007/s00784-026-06899-4
dc.identifier.eid105038373194
dc.identifier.other5d9f4aea-83b8-4e44-9d5e-5168f54e9f7b
dc.identifier.pmcPMC13152877
dc.identifier.pmid42096052
dc.identifier.urihttp://hdl.handle.net/10400.14/57709
dc.identifier.wos001760114900004
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSpringer Verlag
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectGingival recessioneng
dc.subjectPlatelet-rich fibrineng
dc.subjectDigital assessmenteng
dc.subjectRoot coverageeng
dc.subjectPeriodontal plastic surgeryeng
dc.titleTreatment of gingival recession type 1 using coronally advanced flap with leucocytes-platelet rich fibrin: a randomized controlled trial
dc.typeresearch article
dspace.entity.typePublication
oaire.citation.issue220
oaire.citation.volume30
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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