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Health gut microbiota-mediated effects of mushrooms: potential in neuroprotection

2023-02-10Póster não publicado nas atas da conferência Acesso aberto
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dc.contributor.authorAraújo-Rodrigues, Helena
dc.contributor.authorTavaria, Freni K.
dc.contributor.authorRelvas, João Bettencourt
dc.contributor.authorPintado, Manuela E.
dc.date.accessioned2025-09-17T08:25:29Z
dc.date.available2025-09-17T08:25:29Z
dc.date.issued2023-02-10
dc.description.abstractResume: Gut microbiota dysbiosis has been directly connected with several clinical conditions, including neurodegenerative disorders. Many neuroactive molecules produced by intestinal flora such as short-chain fatty acids (SCFAs), gamma-aminobutyric acid (GABA), and serotonin, have been shown to contribute to healthy brain function. Alzheimer’s disease (AD) has been connected with reduced levels of these metabolites. Intestinal microbiota dysbiosis and aging have been associated with increased permeability of the gastrointestinal tract epithelium and blood-brain barrier, resulting in the alteration of transport mechanisms. Gut microbiota modulation has been suggested as a potential tool for AD and diet is believed to be a powerful driver in this modulation. Numerous studies showed the prebiotic potential of mushrooms or mushroom polysaccharide extracts. ?-glucans and other mushroom prebiotic molecules strongly stimulate the production of neuroactive metabolites by gut microbiota. We aimed to assess the state-of-the-art of mushroom prebiotic potential and their neuroprotective gut microbiota-mediated effects.eng
dc.identifier.citationAraújo-Rodrigues, H., Tavaria, F. K., Relvas, J. B., & Pintado, M. E. (2023). Health gut microbiota-mediated effects of mushrooms: potential in neuroprotection. Poster session presented at 2d Symposium on AD: An Update on Pathology and Therapeutics, Porto, Portugal.
dc.identifier.other097f7337-8b11-4a4d-8fae-81df350cafa2
dc.identifier.urihttp://hdl.handle.net/10400.14/54998
dc.language.isoeng
dc.peerreviewedno
dc.rights.uriN/A
dc.titleHealth gut microbiota-mediated effects of mushrooms: potential in neuroprotectioneng
dc.typeconference poster not in proceedings
dspace.entity.typePublication
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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