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Design and characterization of biopolymer-based core–shell particles for sustained release of adenosine in tissue regeneration
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The treatment of chronic wounds remains a formidable challenge in regenerative medicine, necessitating multifunctional biomaterials capable of modulating inflammation, promoting angiogenesis, and enabling sustained drug delivery [1]. This study presents a novel class of core–shell aerogel particles engineered from silk fibroin (SF), silk sericin (SS), and alginate (ALG), designed for the controlled release of adenosine (ADO)—a nucleoside with anti-inflammatory and pro-regenerative properties [2]. Using coaxial prilling and supercritical CO? drying, two architectures were fabricated: SF/ALG cores enveloped by ALG or ALG/SS shells.
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Citação
Bernardes, B. G., Sousa, C., Sellitto, M. R., & Iglesias-Mejuto, A. et al. (2026). Design and characterization of biopolymer-based core–shell particles for sustained release of adenosine in tissue regeneration. 1-1. Poster session presented at 5ª Jornada de IBEROS+, Santiago de Compostela, Spain.
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Licença CC
Sem licença CC