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Is decellularized rabbit dermis a viable option for skin wound healing and regeneration?

dc.contributor.authorRosadas, Marta
dc.contributor.authorSousa, Teresa
dc.contributor.authorSousa, Alda
dc.contributor.authorRibeiro, Viviana P.
dc.contributor.authorOliveira, Ana L.
dc.date.accessioned2025-10-24T10:40:17Z
dc.date.available2025-10-24T10:40:17Z
dc.date.issued2025-09-01
dc.description.abstractBurn wounds remain a significant challenge in medical care, requiring effective wound coverage to restore the skin barrier and promote healing or support skin reconstruction. The use of autologous grafts as substitutes is still the standard treatment, however, it is not suitable for deep and extensive burns (1). Decellularized skin allografts and xenografts have emerged as suitable options, using decellularization to remove the immunogenic material present in the tissue while preserving the ECM components and interesting biomolecules (3). Considering that xenografts source availability is significantly higher and free of ethical concerns, this study describes for the first time a protocol for decellularizing rabbit dermis, leveraging a valuable agro-food by-product which exceeds 5000 skins/day at the world-leading company Cortadoria Nacional de Pêlo, and studies its potential for skin regeneration.eng
dc.identifier.citationRosadas, M., Sousa, T., Sousa, A., & Ribeiro, V. P. et al. (2025). Is decellularized rabbit dermis a viable option for skin wound healing and regeneration?. 1-3. Abstract from 34th European Society for Biomaterials, Italy.
dc.identifier.other6df72fa4-ef3d-42b6-8784-405e1ae3aca7
dc.identifier.urihttp://hdl.handle.net/10400.14/55470
dc.language.isoeng
dc.peerreviewedyes
dc.rights.uriN/A
dc.subjectBiocompatibility
dc.subjectBiological material
dc.subjectin vitro tests
dc.subjectLeachables
dc.subjectSkin
dc.subjectWound healing
dc.titleIs decellularized rabbit dermis a viable option for skin wound healing and regeneration?eng
dc.typeconference object
dspace.entity.typePublication
oaire.citation.endPage3
oaire.citation.startPage1
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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