Repository logo
 
Publication

Modulating cell adhesion to polybutylene succinate biotextile constructs for tissue engineering applications

2017Journal article Restricted access
Simple item page
dc.contributor.authorRibeiro, Viviana P.
dc.contributor.authorAlmeida, Lília R.
dc.contributor.authorMartins, Ana R.
dc.contributor.authorPashkuleva, Iva
dc.contributor.authorMarques, Alexandra P.
dc.contributor.authorRibeiro, Ana S.
dc.contributor.authorSilva, Carla J.
dc.contributor.authorBonifácio, Graça
dc.contributor.authorSousa, Rui A.
dc.contributor.authorOliveira, Ana L.
dc.contributor.authorReis, Rui L.
dc.date.accessioned2017-10-12T15:24:48Z
dc.date.available2017-10-12T15:24:48Z
dc.date.issued2017
dc.description.abstractTextile-based technologies are powerful routes for the production of three-dimensional porous architectures for tissue engineering applications because of their feasibility and possibility for scaling-up. Herein, the use of knitting technology to produce polybutylene succinate fibre-based porous architectures is described. Furthermore, different treatments have been applied to functionalize the surface of the scaffolds developed: sodium hydroxide etching, ultraviolet radiation exposure in an ozone atmosphere and grafting (acrylic acid, vinyl phosphonic acid and vinyl sulphonic acid) after oxygen plasma activation as a way to tailor cell adhesion. A possible effect of the applied treatments on the bulk properties of the textile scaffolds has been considered and thus tensile tests in dry and hydrated states were also carried out. The microscopy results indicated that the surface morphology and roughness were affected by the applied treatments. The X-ray photoelectron spectroscopy and contact angle measurements showed the incorporation of oxygen-containing groups and higher surface free energy as result of the surface treatments applied. The DNA quantification and scanning electron microscopy analysis revealed that these modifications enhanced cell adhesion and altered cell morphology. Generally, sodium hydroxide treatment altered most significantly the surface properties, which in turn resulted in a high number of cells adherent to these surfaces. Based on the results obtained, the proposed surface treatments are appropriate to modify polybutylene succinate knitting scaffolds, influencing cell adhesion and its potential for use in tissue engineering applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRibeiro, V. P., Almeida, L. R., Martins, A. R., Pashkuleva, I., Marques, A. P., Ribeiro, A. S., . . . Reis, R. L. (2017). Modulating cell adhesion to polybutylene succinate biotextile constructs for tissue engineering applications. Journal of Tissue Engineering and Regenerative Medicine, 11(10), 2853-2863pt_PT
dc.identifier.doi10.1002/term.2189pt_PT
dc.identifier.eid84978872476
dc.identifier.eissn1932-7005
dc.identifier.issn1932-6254
dc.identifier.pmid27412323
dc.identifier.urihttp://hdl.handle.net/10400.14/23055
dc.identifier.wos000414287300016
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWiley
dc.relationSERICAMED - Designing Functional Silk-Based Biomaterials for In Situ Periodontal Regeneration.
dc.relationTISSUE2TISSUE-Using Textile Technologies to Develop Innovative 3D Architectures to Be Applied in Bone Tissue Engineering
dc.subjectBiotextilept_PT
dc.subjectScaffoldpt_PT
dc.subjectPolybutylene succinatept_PT
dc.subjectSurface modificationpt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectBiomedicalpt_PT
dc.subjectKnitted structurept_PT
dc.titleModulating cell adhesion to polybutylene succinate biotextile constructs for tissue engineering applicationspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleSERICAMED - Designing Functional Silk-Based Biomaterials for In Situ Periodontal Regeneration.
oaire.awardTitleTISSUE2TISSUE-Using Textile Technologies to Develop Innovative 3D Architectures to Be Applied in Bone Tissue Engineering
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/Investigador FCT/IF%2F00411%2F2013%2FCP1167%2FCT0001/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/PTDC%2FCTM%2F105703%2F2008/PT
oaire.citation.titleJournal of Tissue Engineering and Regenerative Medicinept_PT
oaire.fundingStreamInvestigador FCT
oaire.fundingStream5876-PPCDTI
person.familyNameRibeiro
person.familyNamePashkuleva
person.familyNameMarques
person.familyNameSilva
person.familyNameSousa
person.familyNameReis
person.givenNameDr. Viviana
person.givenNameIva
person.givenNameAlexandra
person.givenNameCarla
person.givenNameRui
person.givenNameRui L.
person.identifier769375
person.identifier832165
person.identifier.ciencia-id9414-CDFB-4371
person.identifier.ciencia-idA61F-4AAC-1C34
person.identifier.ciencia-idD010-9646-F5CA
person.identifier.ciencia-idF418-81A4-F2DA
person.identifier.ciencia-id4A1B-29B7-7A48
person.identifier.ciencia-id6F11-C02E-8B6C
person.identifier.orcid0000-0002-3679-0759
person.identifier.orcid0000-0001-6818-3374
person.identifier.orcid0000-0002-3222-0310
person.identifier.orcid0000-0002-7509-9135
person.identifier.orcid0000-0003-0362-7418
person.identifier.orcid0000-0002-4295-6129
person.identifier.ridA-3670-2019
person.identifier.ridB-1238-2012
person.identifier.ridA-8938-2008
person.identifier.scopus-author-id56104780500
person.identifier.scopus-author-id16837175600
person.identifier.scopus-author-id22035647000
person.identifier.scopus-author-id56119493700
person.identifier.scopus-author-id7102960061
person.identifier.scopus-author-id56861715700
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication143dc77d-a812-46f7-aa77-e4af1be2f7fa
relation.isAuthorOfPublication4728d902-08fb-4b7e-aa97-ddb156173e8c
relation.isAuthorOfPublicationb264da1f-6724-4e79-8e3a-ef99c0b845f0
relation.isAuthorOfPublicationdb3e75ef-4a50-4844-971b-c425bc5b411f
relation.isAuthorOfPublicationc24c2c0b-537b-49a1-8a48-e27156a1ea6f
relation.isAuthorOfPublication7a393e8e-6f6c-424c-9dda-02100315967b
relation.isAuthorOfPublication.latestForDiscovery4728d902-08fb-4b7e-aa97-ddb156173e8c
relation.isProjectOfPublication036ca866-3fa9-4f76-9ff1-f2f5646b6c66
relation.isProjectOfPublication28e69e94-f60b-4c9d-9a11-2f95d0f62014
relation.isProjectOfPublication.latestForDiscovery036ca866-3fa9-4f76-9ff1-f2f5646b6c66

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
20075606.pdf
Size:
582.82 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.44 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CBQF - Contribuições em Revistas Científicas / Contribution to Journals