Repository logo
 
Publication

Impact of gestational diabetes mellitus in the maternal-to-fetal transport of nutrients

2015Journal article Restricted access
Simple item page
dc.contributor.authorAraújo, João Ricardo
dc.contributor.authorKeating, Elisa
dc.contributor.authorMartel, Fátima
dc.date.accessioned2015-05-11T17:06:00Z
dc.date.available2015-05-11T17:06:00Z
dc.date.issued2015
dc.description.abstractGestational diabetes mellitus (GDM) is a metabolic disorder prevalent among pregnant women. This disease increases the risk of adverse perinatal outcomes and diseases in the offspring later in life. The human placenta, the main interface between the maternal and fetal blood circulations, is responsible for the maternal-to-fetal transfer of nutrients essential for fetal growth and development. In this context, the aim of this article is to review the latest advances in the placental transport of macro and micronutrients and how they are affected by GDM and its associated conditions, such as elevated levels of glucose, insulin, leptin, inflammation, and oxidative stress. Data analyzed in this article suggest that GDM and its associated conditions, particularly high levels of glucose, leptin, and oxidative stress, disturb placental nutrient transport and, consequently, fetal nutrient supply. As a consequence, this disturbance may contribute to the fetal and postnatal adverse health outcomes associated with GDM.por
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationARAÚJO, João R. ; KEATING, Elisa ; MARTEL, Fátima - Impact of gestational diabetes mellitus in the maternal-to-fetal transport of nutrients. Current Diabetes Reports. ISSN 1539-0829. Vol. 15, n.º 2 (2015), p. 1-10por
dc.identifier.doi10.1007/s11892-014-0569-y
dc.identifier.eid84921844669
dc.identifier.eissn1539-0829
dc.identifier.issn1534-4827
dc.identifier.pmid25620402
dc.identifier.urihttp://hdl.handle.net/10400.14/17549
dc.identifier.wos000348788800001
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSpringer
dc.relationEFEITO DA DIABETES MELLITUS GESTACIONAL NO TRANSPORTE MATERNO-FETAL DE NUTRIENTES E NO DESENVOLVIMEN-TO PLACENTÁRIO
dc.subjectGestational diabetespor
dc.subjectPlacentapor
dc.subjectTransportpor
dc.subjectNutrientspor
dc.subjectFetal programmingpor
dc.titleImpact of gestational diabetes mellitus in the maternal-to-fetal transport of nutrientspor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEFEITO DA DIABETES MELLITUS GESTACIONAL NO TRANSPORTE MATERNO-FETAL DE NUTRIENTES E NO DESENVOLVIMEN-TO PLACENTÁRIO
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F63086%2F2009/PT
oaire.citation.issue2
oaire.citation.titleCurrent Diabetes Reports
oaire.citation.volume15
person.familyNameKeating
person.familyNameMartel
person.givenNameElisa
person.givenNameFátima
person.identifier517090
person.identifier.ciencia-id2E1C-FAA4-A661
person.identifier.ciencia-id5C14-37B4-FDCA
person.identifier.orcid0000-0002-3904-9907
person.identifier.orcid0000-0002-0525-3416
person.identifier.scopus-author-id35612071300
person.identifier.scopus-author-id7005164101
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
relation.isAuthorOfPublication66ab6fb4-ef6c-43e6-876e-22fdf8a479e2
relation.isAuthorOfPublicationb8800d60-d712-4d4c-8619-4a33ca095ca6
relation.isAuthorOfPublication.latestForDiscovery66ab6fb4-ef6c-43e6-876e-22fdf8a479e2
relation.isProjectOfPublicationed933195-1682-43c4-8388-c8f09c8ce9cb
relation.isProjectOfPublication.latestForDiscoveryed933195-1682-43c4-8388-c8f09c8ce9cb

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
26868770.pdf
Size:
1.04 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
3.44 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CBQF - Contribuições em Revistas Científicas / Contribution to Journals