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Design and bioprinting of decellularized extracellular matrix-based bioinks for skin tissue engineering

dc.contributor.authorBebiano, Luís B.
dc.contributor.authorPresa, Rafaela
dc.contributor.authorSilva, Inês V.
dc.contributor.authorOliveira, Ana L.
dc.contributor.authorCosta, João B.
dc.contributor.authorPereira, Rúben F.
dc.date.accessioned2024-03-13T15:27:42Z
dc.date.available2024-03-13T15:27:42Z
dc.date.issued2024-02-27
dc.description.abstract3D bioprinting is a powerful enabling technology for the automated fabrication of biomimetic constructs for skin modelling and repair with high resolution and reproducibility. Bioinks, which often comprise the combination of cells and printable biomaterials, are essential for bioprinting 3D cell-laden constructs emulating the architecture, composition and function of native skin. Tissue- and organ-specific decellularized extracellular matrix (dECM) materials are assuming a significant role in bioink design owing their capacity to provide native biophysical and biochemical signals that can elicit distinct cellular responses toward tissue development. Herein, we discuss the rational design of dECM-based bioinks, focusing on processing methods to obtain dECM as well as on bioprinting strategies to engineer 3D constructs for applications in wound healing and in vitro skin modelling.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.2217/3dp-2023-0011pt_PT
dc.identifier.eid85186620987
dc.identifier.issn2059-4755
dc.identifier.urihttp://hdl.handle.net/10400.14/44278
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectBiofabricationpt_PT
dc.subjectBioinkspt_PT
dc.subjectBioprintingpt_PT
dc.subjectExtracellular matrixpt_PT
dc.subjectHydrogelspt_PT
dc.subjectSkinpt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectWound healingpt_PT
dc.titleDesign and bioprinting of decellularized extracellular matrix-based bioinks for skin tissue engineeringpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue4pt_PT
oaire.citation.titleJournal of 3D Printing in Medicinept_PT
oaire.citation.volume7pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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