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Analyzing the potential of selected gut commensal strains to produce antimicrobial peptides: phenotypic and in silico approaches

dc.contributor.authorFonseca, M.
dc.contributor.authorMachado, D.
dc.contributor.authorVedor, R.
dc.contributor.authorAndrade, J. C.
dc.contributor.authorGomes, A. M.
dc.contributor.authorBarbosa, J. C.
dc.date.accessioned2024-07-08T16:26:10Z
dc.date.available2024-07-08T16:26:10Z
dc.date.issued2024-07
dc.description.abstractThe World Health Organization estimates that the number of antibiotic resistance-related deaths could reach 10 million by 2050 [1]. Given the dynamics and high diversity of microorganisms that inhabit the gastrointestinal tract, this is the ideal place to discover new antimicrobial peptides (AMP) to replace traditional antibiotics [2]. Among the most extensively studied members are the commensal strains Akkermansia muciniphila DSM 22959 and Faecalibacterium duncaniae DSM 17677, which are reported to have a beneficial impact on intestinal health [3;4]. Antimicrobial peptides are small molecules that act as the first line of defense against microbial invaders, playing a vital role in the innate immune system [5]. One approach to identify new strategies to combat antimicrobial resistance is to evaluate the ability of these bacteria to produce AMP.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.14/45698
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.titleAnalyzing the potential of selected gut commensal strains to produce antimicrobial peptides: phenotypic and in silico approachespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlacePortugalpt_PT
oaire.citation.endPage1pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleEncontro Ciência 2024: +Ciência para Uma Só Saúde e bem-estar globalpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT

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