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Wastewater treatment presents a pressing global challenge, emphasizing the urgent need for more sustainable solutions. In the pursuit of energy and carbon neutrality, microalgal-bacterial granular sludge (MBGS) systems have emerged as a promising alternative, leveraging the symbiotic relationship between microalgae and bacteria within granules in terms of gas exchange. MBGS systems offer efficient treatment but also hold the promise for substantial energy savings and greenhouse gas emissions reduction. The present study aimed to ascertain on the dissolved oxygen threshold required for efficient pollutants removal from coastal aquaculture aiming at water recycling in industrial settings.