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Mineral oil risk assessment: knowledge gaps and roadmap. Outcome of a multi-stakeholders workshop

2021-07Artigo científico Acesso aberto
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dc.contributor.authorHochegger, Andrea
dc.contributor.authorMoret, Sabrina
dc.contributor.authorGeurts, Lucie
dc.contributor.authorGude, Thomas
dc.contributor.authorLeitner, Erich
dc.contributor.authorMertens, Birgit
dc.contributor.authorO'Hagan, Susan
dc.contributor.authorPoças, Fátima
dc.contributor.authorSimat, Thomas J.
dc.contributor.authorPurcaro, Giorgia
dc.date.accessioned2021-05-26T14:39:27Z
dc.date.available2021-05-26T14:39:27Z
dc.date.issued2021-07
dc.description.abstractBackground: In recent years there have been significant advancements in the understanding of mineral oil hydrocarbons (MOH) in foods and their potential risk to health. However, important gaps in knowledge remain, such as the lack of validated and standardized analytical methods for relevant food matrices and gaps in assessing the risk for consumers’ health. Scope & approach: A workshop was organized by the European Branch of the International Life Science Institute to identify knowledge gaps in analytical methods, assessment of exposure, hazard characterisation, and risk assessment of MOH. This work captures the outcome of the workshop and builds upon it by combining the perspectives of the participants with an updated review of the literature to provide a roadmap for future management of the topic. Key findings and conclusions: Most participants to the workshop agreed that the key issue underlying many of the knowledge gaps in the field of MOH risk analysis and management is the lack of standardized, validated analytical methods able to assure good inter-laboratory reproducibility and to enable understanding of MOH occurrence in foods. It has been demonstrated that method EN 16995 used for MOH determination in vegetable oils and fats is not reliable below 10 mg/kg of food. There is also a need for confirmatory methods that provide a detailed characterization of the unresolved complex mixture observed from one-dimensional chromatographic methods. This is required to enable adequate substance identification and quantification for input into risk assessment. A major gap in the exposure estimation is the limited number of surveys covering a wide range of foods and enough samples to detect major sources of contamination other than packaging in paperboard. Data on concentration of MOH fractions in human body needed to determine internal exposure estimates is scarce. Data relating concentration in tissues with personal data, lifestyle, food intake and the use of cosmetics are needed to clarify the complex system of distribution of MOSH in the body and to possibly establish relationship between external and internal exposure. Additional toxicological studies to better characterize the hazards of relevant MOH are required for a better human health risk assessment.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1016/j.tifs.2021.03.021pt_PT
dc.identifier.eid85105585300
dc.identifier.issn0924-2244
dc.identifier.urihttp://hdl.handle.net/10400.14/33280
dc.identifier.wos000691735600012
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectExposure assessmentpt_PT
dc.subjectFood contaminantpt_PT
dc.subjectMineral oil hydrocarbonpt_PT
dc.subjectMOAHpt_PT
dc.subjectMOSHpt_PT
dc.subjectRisk assessmentpt_PT
dc.titleMineral oil risk assessment: knowledge gaps and roadmap. Outcome of a multi-stakeholders workshoppt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage166pt_PT
oaire.citation.startPage151pt_PT
oaire.citation.titleTrends in Food Science and Technologypt_PT
oaire.citation.volume113pt_PT
person.familyNameMoret
person.familyNameLeitner
person.familyNameMertens
person.familyNamePoças
person.familyNamePurcaro
person.givenNameSabrina
person.givenNameErich
person.givenNameBirgit
person.givenNameMaria de Fátima
person.givenNameGiorgia
person.identifier.ciencia-id1513-5F90-0B67
person.identifier.orcid0000-0002-5752-5540
person.identifier.orcid0000-0003-2520-2111
person.identifier.orcid0000-0001-8298-9104
person.identifier.orcid0000-0002-6598-6515
person.identifier.orcid0000-0002-8235-9409
person.identifier.ridB-5658-2014
person.identifier.scopus-author-id7003312659
person.identifier.scopus-author-id7003830567
person.identifier.scopus-author-id55794110300
person.identifier.scopus-author-id15127714500
person.identifier.scopus-author-id35796192100
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication339d497c-7f70-4c66-9415-de5550f58d55
relation.isAuthorOfPublication810d0036-545c-4396-b8c7-5ba69c5e7d1a
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relation.isAuthorOfPublication.latestForDiscovery810d0036-545c-4396-b8c7-5ba69c5e7d1a

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