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Anti-hypertensive activity of horse mackerel pulverized with three different extracts from marine origin

dc.contributor.authorNova, Paulo
dc.contributor.authorCunha, Sara A.
dc.contributor.authorBarros, Diana
dc.contributor.authorRamos, Carlos
dc.contributor.authorCastro, Inês
dc.contributor.authorVaz-Velho, Manuela
dc.contributor.authorPintado, Manuela
dc.contributor.authorGomes, Ana
dc.date.accessioned2023-01-30T16:03:25Z
dc.date.available2023-01-30T16:03:25Z
dc.date.issued2021-07
dc.description.abstractHypertension is a serious risk factor and the most prevalent trigger to fatal cardiovascular diseases such as stroke and myocardial infarction. The marine environment is a unique source of molecules with biological activity such as antioxidant, anti-coagulant and anti-hypertensive activities. In this study, the anti-hypertensive activity of horse mackerel fillets (HMF) pulverized with each of the following marine extracts (derived from enzymatic hydrolysis) were determined: microalgae (Tetraselmis sp. incubated with subtilisin and cellulase), Mussel_Sub (Mytilus galloprovincialis minced and incubated with subtilisin protease) and Mussel_ Pro+Alc (Mytilus galloprovincialis boiled and incubated with Protamex and Alcalase). Horse mackerel fillets were evenly sprayed with each extract and frozen until subsequent analyses. Non-sprayed HMF were used as control. Aqueous extracts were prepared from HMF by sonication. Anti-hypertensive activity was determined by the angiotensin I-converting enzyme (ACE) inhibitory activity method. Data are presented in Table.1 as average±standard deviation of two replicates. Table 1. Anti-hypertensive activity of Horse Mackerel fillets sprayed with Extracts from Marine Origin. Horse mackerel fillet showed by itself an interesting anti-hypertensive profile. Notwithstanding, the tested marine-derived extracts effectively increased its biological potential(up to four-fold), with the best anti-hypertensive profile being achieved with microalgae and Mussel_Pro+Alc extracts. These extracts have an enormous potential to be used in the development of innovative food products that emphasize functionality, convenience, nutrition and health – goal of the project VALORMAR (POCI-024517-FEDER)(PPS1).pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.issn1647-662X
dc.identifier.urihttp://hdl.handle.net/10400.14/40055
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectMarine organismspt_PT
dc.subjectBioactive compoundspt_PT
dc.subjectAnti-hypertensive activitypt_PT
dc.subjectFunctional foodspt_PT
dc.subjectHypertensionpt_PT
dc.titleAnti-hypertensive activity of horse mackerel pulverized with three different extracts from marine originpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage111pt_PT
oaire.citation.issue8pt_PT
oaire.citation.startPage111pt_PT
oaire.citation.titleMilleniumpt_PT
oaire.citation.volume2pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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