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Optimization of antioxidant activity and bioactive compounds extraction of winter savory leaves by high hydrostatic pressure

2020Journal article Restricted access
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dc.contributor.authorMoreira, Sílvia A.
dc.contributor.authorPintado, Manuela E.
dc.contributor.authorSaraiva, Jorge A.
dc.date.accessioned2021-01-29T16:40:56Z
dc.date.available2021-01-29T16:40:56Z
dc.date.issued2020
dc.description.abstractWinter savory is often used in traditional medicine, having several recognized biological properties. This study aimed to evaluate the effect of high pressure-assisted extraction (HPE) and its optimization by response surface methodology to obtain winter savory extracts with a high content of bioactive compounds and high antioxidant activity (the effect of extraction pressure, extraction time, and ethanol concentration were investigated). Results showed that data could be well fitted to second-order polynomial mathematical models for total phenolics, total flavonoids, chlorophylls, carotenoids, and extraction yield, as well as for antioxidant activity. The models predicted optimal conditions ranging 200–500 MPa, extraction time 1–20 min, and ethanol concentration 0–70% (v,v). In comparison with extraction at atmospheric pressure, HPE showed to be more efficient, allowing obtaining an increase of about 40% for all compounds, and an increase of 29, 48, and 70% for antioxidant activity by FRAP, DPPH and ABTS assays, respectively.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationMoreira, S. A., Pintado, M. E., Saraiva, J. A. (2020). Optimization of antioxidant activity and bioactive compounds extraction of winter savory leaves by high hydrostatic pressure. High Pressure Research, 40(4), 543-560pt_PT
dc.identifier.doi10.1080/08957959.2020.1830079pt_PT
dc.identifier.eid85094127110
dc.identifier.eissn1477-2299
dc.identifier.issn0895-7959
dc.identifier.urihttp://hdl.handle.net/10400.14/31819
dc.identifier.wos000581158800001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.relationEvaluation of high-pressure as a novel non-thermal extraction technology to obtain extracts with improved biological activities from medicinal herbs
dc.relationOrganic Chemistry, Natural Products and Food Stuffs
dc.relationAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
dc.relationCentre for Biotechnology and Fine Chemistry
dc.subjectHigh pressure extractionpt_PT
dc.subjectResponse surface methodologypt_PT
dc.subjectBioactive compoundspt_PT
dc.subjectAntioxidant activitypt_PT
dc.subjectWinter savorypt_PT
dc.titleOptimization of antioxidant activity and bioactive compounds extraction of winter savory leaves by high hydrostatic pressurept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEvaluation of high-pressure as a novel non-thermal extraction technology to obtain extracts with improved biological activities from medicinal herbs
oaire.awardTitleOrganic Chemistry, Natural Products and Food Stuffs
oaire.awardTitleAssociated Laboratory for Green Chemistry - Clean Technologies and Processes
oaire.awardTitleCentre for Biotechnology and Fine Chemistry
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F110430%2F2015/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FQUI%2F00062%2F2019/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMulti%2F50016%2F2019/PT
oaire.citation.endPage560pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage543pt_PT
oaire.citation.titleHigh Pressure Researchpt_PT
oaire.citation.volume40pt_PT
oaire.fundingStreamPOR_CENTRO
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMoreira
person.familyNamePintado
person.familyNameSaraiva
person.givenNameSilvia
person.givenNameMaria Manuela
person.givenNameJorge
person.identifier456608
person.identifier.ciencia-idE21A-210C-756F
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.ciencia-idEC16-41A3-01BD
person.identifier.orcid0000-0003-2339-9790
person.identifier.orcid0000-0002-0760-3184
person.identifier.orcid0000-0002-5536-6056
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id56493264800
person.identifier.scopus-author-id7004483898
person.identifier.scopus-author-id35583570500
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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