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White spot lesions: diagnosis and treatment - a systematic review

dc.contributor.authorLopes, Pedro C.
dc.contributor.authorCarvalho, Teresa
dc.contributor.authorGomes, Ana T. P. C.
dc.contributor.authorVeiga, Nelio
dc.contributor.authorBlanco, Letícia
dc.contributor.authorCorreia, Maria José
dc.contributor.authorMello-Moura, Anna Carolina Volpi
dc.date.accessioned2024-01-17T13:56:34Z
dc.date.available2024-01-17T13:56:34Z
dc.date.issued2024-01-09
dc.description.abstractBACKGROUND: White spot lesions represent the first stage of caries and their prevalence has been increasing in recent years, particularly in patients undergoing orthodontic treatment. DIferential diagnosis and lesion activity are essential to decide on the clinical approaches to treatment. The aim of this study is to understand if the new diagnostic tools such as fluorescence, microradiography and computed microtomography have the potential to change the conventional treatment of white spots". METHODS: A systematic search of available studies in the literature was carried out, using PRISMA guidelines, in Pubmed and Scopus electronic databases and manually to identify relevant articles to answer the PICO question: "Do the new diagnostic tools have the potential to change the conventional treatment of white spots?". This systematic review included randomized controlled trials (RCT), cross-sectional and longitudinal studies complying with the following inclusion criteria: (i) studies in humans, (ii) studies about white spot lesions, (iii) studies published between 2012 and 2023, (iv) studies having both diagnosis and treatment and (v) studies with full text available. In this review we excluded other systematic reviews of clinical trials and in vitro studies. The RoB tool was used to assess the risk of bias. RESULTS: The systematic literature search identified 143 potentially relevant references, which after applying the exclusion criteria, resulted in 20 articles. Regarding diagnostic methods, most articles found were based on conventional methods of visual examination (n:10) or fluorescence (n:7). The least referenced diagnostic techniques were based on the use of clinical photographs (n:2), cross-sectional microradiography (n:1) and computed microtomography (n:1). The use of DIAGNOdent was reported by 3 in vitro studies. With regard to therapies, most studies reported the use of infiltrating resin (n:7) and fluoride-based products (n:5). Other studies have reported the use of self-assembling peptide P11-4 (n:1), home care (n:1), casein phosphopeptide-amorphous calcium phosphate (n:2) and hydrochloric acid (n:1). Combination therapies were also considered. CONCLUSION: Diagnostic tool does not have the potential to change the form of treatment, whether it is a conventional method or a more differentiated one.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1186/s12903-023-03720-6pt_PT
dc.identifier.eid85181682935
dc.identifier.issn1472-6831
dc.identifier.pmcPMC10775501
dc.identifier.pmid38195439
dc.identifier.urihttp://hdl.handle.net/10400.14/43647
dc.identifier.wos001140432200009
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectWhite spot lesionpt_PT
dc.subjectDental cariespt_PT
dc.subjectDiagnosispt_PT
dc.subjectTreatmentpt_PT
dc.titleWhite spot lesions: diagnosis and treatment - a systematic reviewpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBMC Oral Healthpt_PT
oaire.citation.volume24pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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