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Silver-containing calcium phosphate materials of marine origin with antibacterial activity

dc.contributor.authorPiccirillo, C.
dc.contributor.authorPullar, R. C.
dc.contributor.authorTobaldi, D. M.
dc.contributor.authorCastro, Paula M. L.
dc.contributor.authorEstevez Pintado, M. M.
dc.date.accessioned2016-04-21T16:22:37Z
dc.date.available2016-04-21T16:22:37Z
dc.date.issued2015
dc.description.abstractHydroxyapatite (Ca10(PO4)6(OH)2 – HAp) is a common material for bone replacement in artificial implants and prostheses, due to its high biocompatibility. In this work we report about the preparation of HAp-based materials of marine origin with antibacterial properties. Bones from cod fish (Gadhus morua) were treated with a dilute AgNO3 solution, to obtain HAp-containing samples with silver as a minor component. The samples were characterised by XRD, FT-IR spectroscopy and SEM, indicating the presence of HAp, β–TCP and some metallic silver. The determination of unit cell parameters, however, indicated that the majority of silver is substituted in the β-TCP lattice in ionic form. The antibacterial activity of these materials was tested towards both Gram-positive and Gram-negative bacterias; results showed that the material is very effective with Gram-negative strains such as Escherichia coli (inactivation rates of 99.82% and 99.999% after 2 and 5 h, respectively) and had a smaller but still significant effect on Gram-positive MRSA (91% inactivation rate). These results show the potentials of these samples as infection-resistant bone replacement materials.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationPICCIRILLO, C… [et al.] - Silver-containing calcium phosphate materials of marine origin with antibacterial activity. Ceramics International. ISSN 0272-8842. Vol. 41, n.º 8 (2015), p. 10152-10159pt_PT
dc.identifier.doi10.1016/j.ceramint.2015.04.116
dc.identifier.eid84930925393
dc.identifier.eissn1873-3956
dc.identifier.issn0272-8842
dc.identifier.urihttp://hdl.handle.net/10400.14/19929
dc.identifier.wos000356549100126
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevier
dc.relationQREN AdI11466
dc.relationUID/CTM /50011/2013
dc.relationENVIRONMENTALLY SUSTAINABLE CERAMICS FOR APPLICATIONS AS MULTIFUNCTIONAL PHOTOCATALYST
dc.subjectNatural hydroxyapatitept_PT
dc.subjectβ-tricalcium phosphatept_PT
dc.subjectSilverpt_PT
dc.subjectAntibacterial
dc.titleSilver-containing calcium phosphate materials of marine origin with antibacterial activitypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleENVIRONMENTALLY SUSTAINABLE CERAMICS FOR APPLICATIONS AS MULTIFUNCTIONAL PHOTOCATALYST
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F86483%2F2012/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/FARH/SFRH%2FBPD%2F97115%2F2013/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PEst-OE%2FEQB%2FLA0016%2F2013/PT
oaire.citation.endPage10159
oaire.citation.issue8
oaire.citation.startPage10152
oaire.citation.titleCeramics International
oaire.citation.volume41
oaire.fundingStreamSFRH
oaire.fundingStreamFARH
oaire.fundingStream3599-PPCDT
person.familyNamePiccirillo
person.familyNamePullar
person.familyNameTobaldi
person.familyNameCastro
person.familyNamePintado
person.givenNameClara
person.givenNameRobert
person.givenNameDavid Maria
person.givenNamePaula
person.givenNameMaria Manuela
person.identifier962551
person.identifier646900
person.identifier2013444
person.identifier456608
person.identifier.ciencia-id391B-75ED-6983
person.identifier.ciencia-idD51F-B2C3-B82C
person.identifier.ciencia-id6515-3493-6B27
person.identifier.ciencia-id7C1F-6C72-354A
person.identifier.ciencia-id2F13-AAE0-3405
person.identifier.orcid0000-0002-6339-716X
person.identifier.orcid0000-0001-6844-4482
person.identifier.orcid0000-0002-0112-8570
person.identifier.orcid0000-0001-8841-6606
person.identifier.orcid0000-0002-0760-3184
person.identifier.ridN-8206-2013
person.identifier.ridM-8241-2013
person.identifier.ridF-5696-2013
person.identifier.scopus-author-id7004621626
person.identifier.scopus-author-id7003296532
person.identifier.scopus-author-id16319626100
person.identifier.scopus-author-id7102781782
person.identifier.scopus-author-id7004483898
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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