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Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency

2020-11-01Journal article Open access
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dc.contributor.authorSousa, Liliana B.
dc.contributor.authorSantos-Costa, Paulo
dc.contributor.authorMarques, Inês A.
dc.contributor.authorCruz, Arménio
dc.contributor.authorSalgueiro-Oliveira, Anabela
dc.contributor.authorParreira, Pedro
dc.date.accessioned2021-02-01T18:40:26Z
dc.date.available2021-02-01T18:40:26Z
dc.date.issued2020-11-01
dc.description.abstractThis review aimed to map the existing patents of double-chamber syringes that can be used for intravenous drug administration and catheter flush. A search was conducted in the Google patents database for records published prior to 28 October 2020, using several search terms related to double-chamber syringes (DCS). Study eligibility and data extraction were performed by two independent reviewers. Of the initial 26,110 patents found, 24 were included in this review. The 24 DCS that were found display two or more independent chambers that allow for the administration of multiple solutions. While some of the DCS have designated one of the chambers as the flushing chamber, most patents only allow for the sequential use of the flushing chamber after intravenous drug administration. Most DCS were developed for drug reconstitution, usually with a freeze-dried drug in one chamber. Some patents were designed for safety purposes, with a parallel post-injection safety sheath chamber for enclosing a sharpened needle tip. None of the DCS found allow for a preand post-intravenous drug administration flush. Given the current standards of care in infusion therapy, future devices must allow for the sequential use of the flushing chamber to promote a pre-administration patency assessment and a post-administration device flush.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSousa, L. B., Santos-Costa, P., Marques, I. A., Cruz, A., Salgueiro-Oliveira, A., Parreira, P. (2020). Brief report on double-chamber syringes patents and implications for infusion therapy safety and efficiency. International Journal of Environmental Research and Public Health, 17(21), 8209pt_PT
dc.identifier.doi10.3390/ijerph17218209pt_PT
dc.identifier.eid85095606858
dc.identifier.issn1660-4601
dc.identifier.pmcPMC7664416
dc.identifier.pmid33172109
dc.identifier.urihttp://hdl.handle.net/10400.14/31833
dc.identifier.wos000588992700001
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectDouble-chamber syringespt_PT
dc.subjectVascular access devicespt_PT
dc.subjectFlushingpt_PT
dc.subjectPatent reviewpt_PT
dc.titleBrief report on double-chamber syringes patents and implications for infusion therapy safety and efficiencypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage8
oaire.citation.issue21pt_PT
oaire.citation.startPage1
oaire.citation.titleInternational Journal of Environmental Research and Public Healthpt_PT
oaire.citation.volume17pt_PT
person.familyNameB. Sousa
person.familyNameCosta
person.familyNameCruz
person.familyNameSalgueiro Oliveira
person.givenNameLiliana
person.givenNamePaulo
person.givenNameArménio
person.givenNameAnabela de Sousa
person.identifier.ciencia-idD11C-5EA4-A3A1
person.identifier.ciencia-idC915-2D9E-3AB7
person.identifier.ciencia-id9315-37D0-0CED
person.identifier.ciencia-id9F13-0F90-218C
person.identifier.orcid0000-0002-8914-6975
person.identifier.orcid0000-0003-0761-6548
person.identifier.orcid0000-0003-3254-3176
person.identifier.orcid0000-0002-8231-8279
person.identifier.ridS-1406-2018
person.identifier.ridU-8490-2017
person.identifier.ridT-5761-2017
person.identifier.scopus-author-id55998469500
person.identifier.scopus-author-id36616218200
person.identifier.scopus-author-id57189511153
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscoveryd0599f8f-8892-40b7-8199-f5e3a923a0e2

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