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Pediococcus pentosaceus SB83 as a potential probiotic incorporated in a liquid system for vaginal delivery

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dc.contributor.authorBorges, S.
dc.contributor.authorTeixeira, P.
dc.date.accessioned2015-05-14T11:24:34Z
dc.date.available2015-05-14T11:24:34Z
dc.date.issued2014
dc.description.abstractPediococcus pentosaceus SB83 is a bacteriocinogenic culture having potential use as a vaginal probiotic. The objective of this study was to evaluate the behaviour of P. pentosaceus SB83 incorporated in a liquid system for eventually formulating a gel for vaginal delivery. The vaginal probiotic incorporated into glycerol was able to survive in simulated vaginal fluid at normal vaginal pH (4.2) and at pH of vaginal infections (5.5 and 6.5). The probiotic can be stored at 4 °C for a longer period of time than at room temperature, however, after 13 weeks of storage at low temperature, there was a total loss of viable cells. The probiotic strain incorporated into glycerol showed bacteriocinogenic activity in simulated vaginal fluid, although the antimicrobial activity against Listeria monocytogenes declined during storage. This study showed the behaviour of P. pentosaceus SB83 in glycerol and in simulated vaginal fluid. However, it is necessary to optimise the formulation to produce an actively probiotic vaginal gel.por
dc.description.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.citationBORGES, Sandra; TEIXEIRA, Paula - Pediococcus pentosaceus SB83 as a potential probiotic incorporated in a liquid system for vaginal delivery. Beneficial Microbes. ISSN 1876-2891. Vol. 5, n.º 4 (2014), p. 421-426por
dc.identifier.doi10.3920/BM2013.0084
dc.identifier.issn1876-2891
dc.identifier.urihttp://hdl.handle.net/10400.14/17597
dc.identifier.wosWOS:000347678300007
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherWageningen Academic Publishers
dc.relationStrategic Project - LA 16 - 2011-2012
dc.subjectBacteriocinpor
dc.subjectDelivery systempor
dc.subjectVaginal probioticpor
dc.titlePediococcus pentosaceus SB83 as a potential probiotic incorporated in a liquid system for vaginal deliverypor
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleStrategic Project - LA 16 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEQB%2FLA0016%2F2011/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F45496%2F2008/PT
oaire.citation.endPage426
oaire.citation.issue4
oaire.citation.startPage421
oaire.citation.titleBeneficial Microbes
oaire.citation.volume5
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStreamSFRH
person.familyNameBorges
person.familyNameTeixeira
person.givenNameSandra
person.givenNamePaula
person.identifier.ciencia-id591F-66D5-8F90
person.identifier.orcid0000-0003-4665-1098
person.identifier.orcid0000-0002-6296-5137
person.identifier.ridJ-8678-2014
person.identifier.scopus-author-id15826021600
person.identifier.scopus-author-id7005895206
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspor
rcaap.typearticlepor
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relation.isAuthorOfPublicationb918d4a2-b9f9-4c56-8318-111625e4d58b
relation.isAuthorOfPublication.latestForDiscoveryb918d4a2-b9f9-4c56-8318-111625e4d58b
relation.isProjectOfPublication649dc879-e68a-45df-bcc4-1e66a0521a49
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